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Endocrinology Update Fall 2016

In this issue of Endocrinology Update, learn about the new division chief, community outreach and education, familial isolated pituitary adenomas, telemedicine for diabetes care in rural areas, discovery of a new obesity-risk variant, and new division faculty.

Educational objectives:

Upon completion of this activity, participants should be able to:

  • Become familiar with access challenges facing patients who need endocrinology consultation  
  • Review some ways technology can help to address some of the access issues in medicine 
  • Be aware that there is evidence supporting team care delivered via telemedicine 
  • Recognize the relationship between this new “thrifty” variant and metabolic phenotypes 
  • Recognize some of the most common hypotheses for the pathogenesis of obesity 
  • Recognize the fundamentals of obesity treatment and the potential clinical implications of the “thrifty” variant

 Reading Resources:

  1. Vigersky et al. The Clinical Endocrinology Workforce: Current Status and Future Projections of Supply and Demand. J Clin Endocrinol Metab. 2014; 99(9): 3112–3121.
  2. Lu H et al. Population-based geographic access to endocrinologist in the United States, 2012. BMC Health Serv Res. 2015; 15:541.
  3. Toledo F GS, Ruppert K,  Huber KA, Siminerio L. Efficacy of the Telemedicine for Reach, Treatment, and Access Model (TREAT) Model for Diabetes Care.  Diabetes Care. 2014; 37: e179-e180.
  4. Minster RL, Hawley NL, Su CT, Sun G, Kershaw EE, Cheng H, Buhule OD, Lin J, Reupena MS, Viali S, Tuitele J, Naseri T, Urban Z, Deka R, Weeks DE, McGarvey ST. A thrifty variant in CREBRF strongly influences body mass index in Samoans. Nat Genet. 2016 Sep;48(9):1049-54. doi: 10.1038/ng.3620. Epub 2016 Jul 25.
  5. Loos RJ. CREBRF Variant Increases Obesity Risk and Protects Against Diabetes in Samoans. Nat Genet. 2016; 48(9):976-8.
  6. Neel JV. Diabetes Mellitus: a “Thrifty” Genotype Rendered Detrimental by “Progress”? Am J Hum Genet. 1962; 14: 353–362.
  7. Gosling AL, Buckley HR, Matisoo-Smith E, Merriman TR. Pacific Populations, Metabolic Disease, and “Just-so Stories’: A Critique of the ‘Thrifty Genotype’ Hypothesis in Oceania. Ann Hum Genet. 2015; 79(6): 470-80.


All contributing authors report no relationships with proprietary entities producing health care goods or services.

All presenters disclosure of relevant financial relationships with any entity producing, marketing, re-selling, or distributing health care goods or services, used on, or consumed by, patients is listed above.  No other planners, members of the planning committee, speakers, presenters, authors, content reviewers and/or anyone else in a position to control the content of this education activity have relevant financial relationships to disclose.

Accreditation Statement:

The University of Pittsburgh School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The University of Pittsburgh School of Medicine designates this enduring material for a maximum of .5 AMA PRA Category 1 Credits™. Each physician should only claim credit commensurate with the extent of their participation in the activity. Other health care professionals are awarded (0.05) continuing education units (CEU) which are equivalent to .5 contact hour.

For your credit transcript, please access our website 4 weeks post-completion at http://ccehs.upmc.edu and follow the link to the Credit Transcript page. If you do not provide the last 5 digits of your SSN on the next page you will not be able to access a CME credit transcript. Providing your SSN is voluntary.

Release Date: 5/10/2014 | Last Modified On: 10/25/16 | Expires: 10/25/17

Additional Resources


Erin E Kershaw, MD

Erin E Kershaw, MD Dr. Erin Kershaw practices at UPMC and is currently an Assistant Professor of Medicine in the Division of Endocrinology at The University of Pittsburgh in Pittsburgh, PA. Dr. Kershaw obtained her Bachelor of Arts degree with honors from Cornell University, Ithaca, NY in 1991. She obtained her ...
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Linda Siminerio, RN, PhD

Linda Siminerio, RN, PhD Dr. Siminerio’s primary research topics include diabetes education, diabetes translation into community interventions, pediatric diabetes care and education, and the psychosocial and behavioral aspects of diabetes.
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Pooja Manroa, MD

Pooja Manroa, MD UPMC Endocrinology and Diabetes Center
Falk Medical Building
3601 Fifth Ave.
Suite 3B
Pittsburgh, PA 15213
Office Phone: (412) 586-9700
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Sue Challinor, MD

Sue Challinor, MD UPMC Endocrinology and Diabetes Center
Falk Medical Building
3601 Fifth Ave.
Suite 3B
Pittsburgh, PA 15213
Office Phone: (412) 586-9700
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Michelle L Griffith, MD

Michelle L Griffith, MD Michelle L. Griffith, MD, is an endocrinologist with UPMC’s Center for Diabetes and Endocrinology, as well as a clinical assistant professor of medicine in the Division of Endocrinology and Metabolism, at the University of Pittsburgh School of Medicine.
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