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Personalized Medicine in Lung Transplantation

Cynthia Gries, MD, provides an overview of personalized medicine and its use in lung transplant. Topics of discussion include candidate selection, allocation, pharmacokinetics, and surveillance and prevention.

Educational objectives:

Upon completion of this activity, participants should be able to:

  • Describe ways that personalized medicine can be used in candidate selection
  • Assess the potential uses of personalized medicine in organ allocation
  • Identify potential uses of personalized medicine in surveillance and prevention of disease after transplant

Reading Resources:

  1. Lung Transplantation in Patients with Prior Cardiothoracic Surgical Procedures.Shigemura N, Bhama J, Gries CJ, Kawamura T, Crespo M, Johnson B, Zaldonis D, Pilewski J, Toyoda Y, Bermudez C.Am J Transplant. 2012 Feb 2. doi: 10.1111/j.1600-6143.2011.03946.x. [Epub ahead of print]
  2. Lung Transplantation for Patients With High Lung Allocation Score: Single-Center Experience. Horai T, Shigemura N, Gries C, Pilewski J, Bhama JK, Bermudez CA, Zaldonis D, Toyoda Y. Ann Thorac Surg. 2011 Dec 20. [Epub ahead of print]
  3. Development of a predictive model for long-term survival after lung transplantation and implications for the lung allocation score. Gries CJ, Rue TC, Heagerty PJ, Edelman JD, Mulligan MS, Goss CH. J Heart Lung Transplant. 2010 Jul;29(7):731-8. Epub 2010 Apr 9.

Disclosures:

Dr. Gries has financial interests with the following proprietary entity or entities producing health care goods or services:

Grant/Research Support: NIH/NCCR/KL2 grant

Accreditation Statement:

The University of Pittsburgh School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The University of Pittsburgh School of Medicine designates this enduring material for a maximum of 0.5 AMA PRA Category 1 CreditsTM. Each physician should only claim credit commensurate with the extent of their participation in the activity. Other health care professionals are awarded (0.05) continuing education units (CEU) which are equivalent to 0.5 contact hours.

For your credit transcript, please access our website 4 weeks post-completion at http://ccehs.upmc.edu and follow the link to the Credit Transcript page. If you do not provide the last 5 digits of your SSN on the next page you will not be able to access a CME credit transcript. Providing your SSN is voluntary.

Release Date: 3/15/2012 | Last Modified On: 6/26/2012 | Expires: 6/26/2014

Presenter

Cynthia Jane Gries, MD

Cynthia Jane Gries, MD Cynthia Gries completed medical school at University of Chicago Pritzker School of Medicine. In addition to completing her Internal Medicine residency training at Johns Hopkins Hospital and her Pulmonary and Critical Care Medicine fellowship at the University of Washington (UW), Dr. Gries ...
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