UPMC Physician Resources
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Sepsis: Systemic inflammation gone wrong
Dr. Derek Angus discusses the strengths and weaknesses of current pathophysiological models in the management and treatment of systematic sepsis in the hospital setting.
Educational Objectives:
Upon completion of this activity, participants should be able to:
- Recognize clinical definitions and current trends in the epidemiology of severe sepsis
- Assess strengths and weaknesses of current pathophysiologic models of sepsis
- Apply current data on outcomes from severe sepsis
Reading Resources:
- Sepsis: Something old, something new, and a systems view. Namas R, Zamora R, Namas R, An G, Doyle J, Dick TE, Jacono FJ, Androulakis IP, Nieman GF, Chang S, Billiar TR, Kellum JA, Angus DC, Vodovotz Y. J Crit Care. 2011 Jul 26. [Epub ahead of print]
- The lingering consequences of sepsis: a hidden public health disaster? Angus DC. JAMA. 2010 Oct 27;304(16):1833-4.
- The Surviving Sepsis Campaign: results of an international guideline-based performance improvement program targeting severe sepsis. Levy MM, Dellinger RP, Townsend SR, Linde-Zwirble WT, Marshall JC, Bion J, Schorr C, Artigas A, Ramsay G, Beale R, Parker MM, Gerlach H, Reinhart K, Silva E, Harvey M, Regan S, Angus DC.Intensive Care Med. 2010 Feb; 36(2):222-31. Epub 2010 Jan 13. Review.
Disclosures:
Dr. Angus receives grant/research support from and is a consultant for Eisai, Inc. He is also a consultant for ALung and ZD Associates. Finally, he is a member of the DSMB for Eli Lilly.
Accreditation Statement:
The University of Pittsburgh School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
The University of Pittsburgh School of Medicine designates this enduring material for a maximum of 0.5 AMA PRA Category 1 CreditsTM. Each physician should only claim credit commensurate with the extent of their participation in the activity. Other health care professionals are awarded (0.05) continuing education units (CEU) which are equivalent to 0.5 contact hours.
For your credit transcript, please access our website 4 weeks post-completion at http://ccehs.upmc.edu and follow the link to the Credit Transcript page. If you do not provide the last 5 digits of your SSN on the next page you will not be able to access a CME credit transcript. Providing your SSN is voluntary.
Release Date: 1/19/2012 | Last Modified On: 1/19/2012 | Expires: 1/19/2013
Dr. Derek C. Angus is professor and chair, Critical Care Medicine and professor, Medicine and Health Policy and Management at the University of Pittsburgh School of Medicine and UPMC. He also is the director of the Clinical Research, Investigation and Systems Modeling of Acute Illness (CRISMA) ...