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Dr. Kenneth Fasanella discusses patient outcome data for patient receiving ablative therapy for Barrett’s esophagus and the risk of cancer progression at various levels of dysplasia.

Educational Objectives:

Upon completion of this activity, participants should be able to:

  • Improve knowledge of the latest data on risk of progression in Barrett’s esophagus with dysplasia
  • Improve outcomes for patients with dysplasia by referring for ablation
  • Improve outcomes of patients with early esophageal cancer by referral to expert esophagologist for risk stratification

Reading Resources:

  1. Zooming in on Barrett’s esophagus using narrow-band imaging: an international observer agreement study.  Herrero LA, Curvers WL, Bansal A, Wani S, Kara M, Schenk E, Schoon EJ, Lynch Cr, Rastogi A, Pondugula K, Weusten B, Sharma P, Bergman JJ.  Eur J Gastroenterol Hepatol 2009 Sep; 21(9):1068-75.
  2. Curative endoscopic resection of early esophageal adenocarcinomas (Barrett's cancer). Ell C, May A, Pech O, Gossner L, Guenter E, Behrens A, Nachbar L, Huijsmans J, Vieth M, Stolte M. Gastrointest Endosc. 2007 Jan;65(1):3-10.
  3. Radiofrequency ablation in Barrett’s esophagus with dysplasia Shaheen NJ, Sharma P, Overholt BF, Wolfsen HC, Sampliner RE, Wang KK, Galanko JA, Bronner MP, Goldblum JR, Bennett AE, Jobe BA, Eisen GM, Fennerty MB, Hunter JG, Fleischer DE, Sharma VK, Hawes RH, Hoffman BJ, Rothstein RI, Gordon SR, Mashimo H, Chang KJ, Muthusamy VR, Edmundowicz SA, Spechler SJ, Siddiqui AA, Souza RF, Infantolino A, Falk GW, Kimmey MB, Madanick RD, Chak A, Lightdale CJ..  N Engl J Med. 2009 May 28;360(22):2277-88.
  4. American Gastroenterological Association medical position statement on the management of Barrett’s esophagus. Spechler SJ, Sharma P, Souza RF, Inadomi JM, Shaheen NJ. Gastroenterology.  2011 Mar;140(3):1084-91.


Dr. Fasanella has no relevant financial interests with any entity or entities producing health care goods or services.

Accreditation Statement:

The University of Pittsburgh School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The University of Pittsburgh School of Medicine designates this enduring material for a maximum of 0.50 AMA PRA Category 1 CreditsTM. Each physician should only claim credit commensurate with the extent of their participation in the activity. Other health care professionals are awarded (0.05) continuing education units (CEU) which are equivalent to 0.50 contact hour.

For your credit transcript, please access our website 4 weeks post-completion at and follow the link to the Credit Transcript page. If you do not provide the last 5 digits of your SSN on the next page you will not be able to access a CME credit transcript. Providing your SSN is voluntary.

Release Date: 11/27/2012 | Last Modified On: 12/15/2013 | Expires: 12/15/2014

This course has been expired.