You are viewing the 1st of the 2 courses UPMC Physician Resources permits you to view without registering. To have full access to our FREE courses on our website, please register or log in now.

Dr. Alexandre Dombrovski presents a series of finding from a behavioral and imaging reduction studies of decision making in late in life suicide. These studies aim to understand what prompts people to favor suicide in a crisis over alternative solutions and to reject deterrence.

Educational objectives:

Upon completion of this activity, participants should be able to:

  • Recognize the contribution of impaired decision-making to suicidal behavior.
  • Recognize neural circuits involved in decision-making
  • Recognize neural circuit alterations that may contribute to impaired decision-making in suicidal individuals.

Reading Resources:

  1. DOMBROVSKI AY, SZANTO K., CLARK L, REYNOLDS 3RD CF, SIEGLE, GJ. Reward signals, impulsivity, and attempted suicide in late-life depression. JAMA Psychiatry, 2013 Aug 7.
  2. DOMBROVSKI AY, SZANTO K, SIEGLE GJ, WALLACE ML, FORMAN SD, SAHAKIAN B, REYNOLDS CF 3RD, CLARK L. Lethal forethought: delayed reward discounting differentiates high- and low-lethality suicide attempts in old age. Biol Psychiatry. 2011 Jul;70(2):138-144.
  3. SZANTO, K, BRUINE DE BRUIN, WJA, PARKER, AM, HALLQUIST, MN, VANYUKOV, PM AND DOMBROVSKI, AY (2015) Decision-making competence and attempted suicide. Journal of Clinical Psychiatry. ISSN 0160-6689 (In Press)


Dr. Dombrovski has reported no relevant relationships with any entities producing health care goods or services.

Accreditation Statement:

The University of Pittsburgh School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. 

The University of Pittsburgh School of Medicine designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credits™. Each physician should only claim credit commensurate with the extent of their participation in the activity. Other health care professionals are awarded (0.1) continuing education units (CEU) which are equivalent to 1.0 contact hour.

For your credit transcript, please access our website 4 weeks post-completion at and follow the link to the Credit Transcript page. If you do not provide the last 5 digits of your SSN on the next page you will not be able to access a CME credit transcript. Providing your SSN is voluntary.

Release Date: 3/2/2016 | Last Modified On: 3/2/2016 | Expires: 3/29/2017

This course has been expired.