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Transplant recipients are at higher risk for viral infections. When compared with the general population, they shed virus and become infected more frequently, are more likely to develop more severe disease, and may respond more slowly to standard therapy. This discussion will focus on the more common human herpes viral infections affecting kidney transplant recipients, highlighting recent advances in the prevention and treatment of disease.

Educational objectives:

Upon completion of this activity, participants should be able to

  • List common human herpes virus (HHV) infections affecting kidney transplant recipients and transplant specific risk factors that increase the risk for infection.
  • Choose appropriate preventive strategies for HHV infections in kidney transplant recipients.
  • Choose appropriate diagnostic tests and treatments for HHV infections in kidney transplant recipients.

Reading Resources:

  1. Weikert, BC and Blumberg, EA.  Viral Infection after Renal Transplantation:  Surveillance and Management.  Clin J Am Soc Nephrol 3:  276-86, 2008.
  2. Razonable RR, Humar A, Practice ASTIDCo. Cytomegalovirus in solid organ transplantation. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 2013 Mar;13 Suppl 4:93-106.
  3. Rubin LG, Levin MJ, Ljungman P, Davies EG, Avery R, Tomblyn M, et al. 2013 IDSA clinical practice guideline for vaccination of the immunocompromised host. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2014 Feb;58(3):309-18.


Doctors Dorneich, Wu and Berrios have reported no relevant relationships with any entities producing health care goods or services.

Accreditation Statement:

The University of Pittsburgh School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The University of Pittsburgh School of Medicine designates this enduring material for a maximum of .5 AMA PRA Category 1 Credits™. Each physician should only claim credit commensurate with the extent of their participation in the activity. Other health care professionals are awarded (0.05) continuing education units (CEU) which are equivalent to .5 contact hour.

For your credit transcript, please access our website 4 weeks post-completion at and follow the link to the Credit Transcript page. If you do not provide the last 5 digits of your SSN on the next page you will not be able to access a CME credit transcript. Providing your SSN is voluntary.

Release Date: 2/22/2016 | Last Modified On: 2/22/2016 | Expires: 2/22/2017

This course has been expired.