Dr. Igor Nasonkin presents an overview of retinal cell plasticity and stem cell therapies for treating blindness.

Educational objectives:

Upon completion of this activity, participants should be able to:

  • Review stem cells, including different types
  • Discuss epigenitics
  • Describe cell replacement approach in the retina

Reading Resources:

  1. Hambright D, Park KY, Brooks M, McKay R, Swaroop A, Nasonkin IO. Long-term survival and differentiation of retinal neurons derived from human embryonic stem cell lines in un-immunosuppressed mouse retina. Mol Vis. 2012;18:920-36. Epub 2012 Apr 12.
  2. Nasonkin I, Mahairaki V, Xu L, Hatfield G, Cummings BJ, Eberhart C, Ryugo DK, Maric D, Bar E, Koliatsos VE. Long-term, stable differentiation of human embryonic stem cell-derived neural precursors grafted into the adult mammalian neostriatum. Stem Cells. 2009 Oct;27(10):2414-26. doi: 10.1002/stem.177.
  3. Mahairaki V, Lim SH, Christopherson GT, Xu L, Nasonkin I, Yu C, Mao HQ, Koliatsos VE. Nanofiber matrices promote the neuronal differentiation of human embryonic stem cell-derived neural precursors in vitro.Tissue Eng Part A. 2011 Mar;17(5-6):855-63

Disclosures:

Dr. Nasonkin has financial interests with the following any entity or entities producing health care goods or services as indicated below:

  • Grant/Research Support: Startup & Retinal Stem Cell Consortium/NYStem

Accreditation Statement:

The University of Pittsburgh School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The University of Pittsburgh School of Medicine designates this enduring material for a maximum of .5 AMA PRA Category 1 Credits™. Each physician should only claim credit commensurate with the extent of their participation in the activity. Other health care professionals are awarded (0.05) continuing education units (CEU) which are equivalent to 0.5 contact hour.

For your credit transcript, please access our website 4 weeks post-completion at http://ccehs.upmc.edu and follow the link to the Credit Transcript page. If you do not provide the last 5 digits of your SSN on the next page you will not be able to access a CME credit transcript. Providing your SSN is voluntary.

Release Date: 12/23/2013 | Last Modified On: 12/23/2013 | Expires: 12/23/2014

This course has been expired.