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Dr. Bernhard Kühn, MD, pediatric cardiologist at Children’s Hospital of Pittsburgh of UPMC, presents a brief case scenario to highlight some of the issues that are being faced in pediatric cardiology.

Educational objectives:

  • Closely follow development of new pediatric-specific medical heart failure therapies
  • Have knowledge about latest research results about mechanisms of post-natal heart growth

Reading Resources:

  1. Mollova, M., Bersell, K., Walsh, S., Savla, J., Das, L.T., Park, S.Y., Silberstein, L.E., Dos Remedios, C.G., Graham, D., Colan, S. & Kuhn, B. Cardiomyocyte proliferation contributes to heart growth in young humans. Proceedings of the National Academy of Sciences of the United States of America 110, 1446-1451 (2013).
  2. Wadugu, B. & Kuhn, B. The role of neuregulin/ErbB2/ErbB4 signaling in the heart with special focus on effects on cardiomyocyte proliferation. Am J Physiol Heart Circ Physiol 302, H2139-2147 (2012).
  3. Senyo, S.E., Steinhauser, M.L., Pizzimenti, C.L., Yang, V.K., Cai, L., Wang, M., Wu, T.D., Guerquin-Kern, J.L., Lechene, C.P. & Lee, R.T. Mammalian heart renewal by pre-existing cardiomyocytes. Nature 493, 433-436 (2013).


Dr. Kuhn has reported no relevant relationships with any entities producing health care goods or services.

Accreditation Statement:

The University of Pittsburgh School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The University of Pittsburgh School of Medicine designates this enduring material for a maximum of 1 AMA PRA Category 1 Credits™. Each physician should only claim credit commensurate with the extent of their participation in the activity. Other health care professionals are awarded (0.1) continuing education units (CEU) which are equivalent to 1 contact hour.

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Release Date: 10/22/15 | Last Modified On: 10/22/15 | Expires: 10/24/15

This course has been expired.