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The treatment of myositis is challenging forboth internists and rheumatologists and its rarity and heterogeneity add further complexity. This review from UPMCRheumatology Grand Rounds discusses both conventional and some newer agents in treating myositis.


To open the document in the page viewer, click the "Read More" button above (note: due to recent changes to the Firefox browser, IE, Chrome or Safari is necessary to access the page viewer). To receive CME Credit once you’ve finished reading the document, please complete the following steps:

  1.     Close the document window and return to the course page.
  2.     Click the orange “Take the CME Evaluation” button.
  3.     Complete the registration, evaluation and the post-test pages.

An electronic certificate will be issued and your participation recorded in our database. Please print the certificate and keep it for your records.

Educational Objectives:

Upon completion of this activity, participants should be able to:

  1. Identify the most common antibody found in myositis.
  2. List three immunosuppressive drugs used to treat myositis.
  3. Examine several conditions that require special treatment considerations regarding patients with myositis. 

Reading Resources:

Rheum Dis Clin North Am. 2011 Nov;37(4):607-21. Epub 2011 Oct 24.
Paraneoplastic myalgias and myositis.
Aggarwal R, Oddis CV.
Division of Rheumatology and Clinical Immunology, University of Pittsburgh, 3601 5th Avenue, Suite 2B, 243, Pittsburgh, PA 15213, USA

Rheumatology (Oxford). 2011 Dec;50(12):2155-6. Epub 2011 May 13.
Rituximab in myositis.
Aggarwal R.
Department of Medicine, Division of Rheumatology, University of Pittsburgh, BST 727 S, 3500 Terrace street, Pittsburgh, PA 15262, USA.

Curr Rheumatol Rep. 2011 Jun;13(3):182-91.
Therapeutic approaches in myositis.
Aggarwal R, Oddis CV.
Division of Rheumatology and Clinical Immunology, Department of Medicine, University of Pittsburgh, BST S 727, 3500 Terrace Street, Pittsburgh, PA 15261, USA.


Dr. Oddis is a consultant for Questcor. Dr. Aggarwal is a consultant for  Atye Pharma.

Accreditation Statement:

The University of Pittsburgh School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The University of Pittsburgh School of Medicine designates this enduring material for a maximum of 1.0 AMA PRA Category 1 CreditsTM. Each physician should only claim credit commensurate with the extent of their participation in the activity. Other health care professionals are awarded (0.1) continuing education units (CEU) which are equivalent to 1.0 contact hours.

For your credit transcript, please access our website 4 weeks post-completion at and follow the link to the Credit Transcript page. If you do not provide the last 5 digits of your SSN on the next page you will not be able to access a CME credit transcript. Providing your SSN is voluntary.

Release Date: 12/1/2011 | Last Modified On: 7/23/2013 | Expires: 7/23/2014

This course has been expired.