Living-Donor Liver Transplant Protocols

At the UPMC Liver Transplant Program, our team partners with referring physicians to evaluate patients and provide liver transplant services to all who will benefit, which includes those who qualify for a deceased donor transplant given the complexity of their disease, such as patients with liver cancer or low MELD.

Living-Donor Liver Transplant for Patients with Complex Liver Cancers

Living-donor liver transplant provides a life-sustaining treatment option for patients with liver cancer who have exhausted all other treatment options.

Our experts have developed innovative protocols for the following types of liver cancer:

  • Unresectable metastatic colorectal cancer
  • Hepatocellular carcinoma
  • Intrahepatic cholangiocarcinoma or mixed cholangio/hepatocellular carcinoma 
  • Hilar cholangiocarcinoma
  • Unresectable neuroendocrine tumor with LDLT

Living-Donor Liver Transplant for Patients with Low MELD Scores

Living-donor liver transplant is a first-line treatment option for patients with traditional or complex liver conditions. Any patient with liver decompensation irrespective of their MELD score should still be considered for a liver transplant, including those diagnosed with:

  • ABO incompatible living donor liver transplant
  • Acute liver failure
  • Alcoholic hepatitis
  • Bloodless medicine or bloodless surgery
  • HIV recipients
  • Low/ high MELD patients
  • Re-do liver transplants
  • Simultaneous liver kidney

Novel Indications Brochure (PDF)

Early access to a liver transplant allows patients to avoid suffering from chronic liver disease, which over time can lead to deteriorating health, multiple medical interventions, and hospitalizations.

Contact the team at the UPMC Liver Transplant Program.