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UPMC has been selected as a center for the ReChord trial (Randomized Trial of the Neochord DS1000 System Versus Open Surgical Repair). The objective of the ReChord trial is to assess the safety and effectiveness of the Neochord DS1000 System in subjects with moderate to severe degenerative mitral regurgitation receiving mitral valve repair without cardiopulmonary bypass. It will compare outcomes of the Neochord DS1000 system to traditional mitral valve surgery.
The first line treatment of mitral regurgitation, particularly for mitral valve prolapse, is valve repair surgery. The Neochord DS1000 system allows for a beating heart, sternal sparing mitral valve repair using an artificial chordae tendineae. The procedure is done via transapical approach.
Potential candidates have the following characteristics: