SERENADE Clinical Study

A study to evaluate how effective and safe macitentan is on subjects with heart failure with preserved ejection fraction.

Participants must be male or female 18 years or older, have signs of heart failure (swelling in your feet or belly, short of breath with activity), and have a preserved ejection fraction of 40% or greater.

If you know a patient you believe may qualify, please call Kristin Shoemaker RN, BSN, research nurse coordinator at 412-647-4463 or email