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Dr. Kyle Ansel Soltys discusses the evolution of Hepatocyte Transplantations as well as methods and strategies for pediatric liver transplantation.

Educational objectives:

Upon completion of this activity, participants should be able to:

  • Discuss current strategies for pediatric liver transplantation
  • Describe the theory and methods of hepatocyte transplantation
  • Discuss the use of hepatocyte transplantation in acute liver failure and metabolic disorders

Reading Resources:

  1. Allospecific CD154 + T-cytotoxic memory cells as potential surrogate for rejection risk in pediatric intestine transplantation. Sindhi R, Ashokkumar C, Higgs BW, Gilbert PB, Sun Q, Ranganathan S, Jaffe R, Snyder S, Ningappa M, Soltys KA, Bond GJ, Mazariegos GV, Abu-Elmagd K, Zeevi A. Pediatr Transplant. 2012 Feb;16(1):83-91. doi: 10.1111/j.1399-3046.2011.01617.x. Epub 2011 Nov 29
  2. Roles of hepatocyte and myeloid CXC chemokine receptor-2 in liver recovery and regeneration after ischemia/reperfusion. Van Sweringen HL, Sakai N, Quillin RC, Bailey J, Schuster R, Blanchard J, Goetzman H, Caldwell CC, Edwards MJ, Lentsch AB.  Hepatology. 2012 Sep 7. doi: 10.1002/hep.26049. [Epub ahead of print]
  3. Acute liver failure in children. Devictor D, Tissieres P, Afanetti M, Debray D. Clin Res Hepatol Gastroenterol. 2011 Jun;35(6-7):430-7. Epub 2011 Apr 30. Review


Dr. Soltys has no relevant relationships with any entities producing health care goods or services

Accreditation Statement:

The University of Pittsburgh School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The University of Pittsburgh School of Medicine designates this enduring material for a maximum of 0.50 AMA PRA Category 1 CreditsTM. Each physician should only claim credit commensurate with the extent of their participation in the activity. Other health care professionals are awarded (0.05) continuing education units (CEU) which are equivalent to 0.50 contact hour.

For your credit transcript, please access our website 4 weeks post-completion at and follow the link to the Credit Transcript page. If you do not provide the last 5 digits of your SSN on the next page you will not be able to access a CME credit transcript. Providing your SSN is voluntary.

Release Date: 11/1/2012 | Last Modified On: 12/15/2013 | Expires: 12/15/2014

This course has been expired.