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Pediatric neurosurgeon, Dr. Ian Frederic Pollack, discusses immunotherapy for the management of pediatric brainstem gliomas with an evaluation of the potential role of immunotherapy as anadjunct therapy for the tumors.

Educational objectives:

Upon completion of this activity, participants should be able to:

  • Gain familiarity with current management and outcome of pediatric brainstem gliomas
  • Discuss current management and outcomes of pediatric high-grade gliomas
  • Evaluate the potential role of immunotherapy as a novel therapeutic adjunct for pediatric gliomas

Reading Resources:

  1. Pollack IF. Current Concepts: Brain tumors in children, N Engl J Medicine 331: 1500-1507, 1994.
  2. Okada J, Kalinski P, Ueda R, Hoji A, Kohanbash G, Donegan TE, Mintz AH, Engh JA, Barlett DL, Brown C, Zeh H, Holtzmann MP, Whiteside TL, Butterfield LH, Hamilton RL, Potter DM, Pollack IF, Salazar AM, Lieberman FS. Induction of CD8+ T cell responses against novel glioma-associated antigen peptides and clinical activity by vaccinations with a-type-1-polarized dendritic cells and poly-ICLC in patients with recurrent malignant glioma. J Clin Oncol 29: 330-336, 2011.
  3. Okada H, Pollack IF. Do we need novel radiological response criteria for brain tumor immunotherapy? Expert Rev Neurother 11:  619-622, 2011.


Dr. Pollack has financial interests with the following any entity or entities producing health care goods or services as indicated below:

  • Stockholder: Former passive holder of Pfizer, Biogen, Forest Labs and United Health Group stock (by inheritance) – these have since been sold

Accreditation Statement:

The University of Pittsburgh School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The University of Pittsburgh School of Medicine designates this enduring material for a maximum of 0.75 AMA PRA Category 1 CreditsTM. Each physician should only claim credit commensurate with the extent of their participation in the activity. Other health care professionals are awarded (0.075) continuing education units (CEU) which are equivalent to 0.75 contact hours.

For your credit transcript, please access our website 4 weeks post-completion at and follow the link to the Credit Transcript page. If you do not provide the last 5 digits of your SSN on the next page you will not be able to access a CME credit transcript. Providing your SSN is voluntary.

Release Date: 4/12/2012 | Last Modified On: 7/8/2013 | Expires: 7/8/2014

This course has been expired.