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UPMC psychiatrist, Dr. Charles Reynolds, discusses the link between late-life depression and future dementia in this recent presentation of the outcomes of the MTLD-III trial. This presentation was part of the speaker series presented by the Aging Institute of UPMC Senior Services and the University of Pittsburgh.

Learning Goals and Objective

After completing this course, participants will:

  • Specify the relationships between depression and dementia in older adults
  • Identify the clinical manifestations and significance of mild cognitive impairment in older adults with major depression
  • List the benefits and risks of adjunctive cholinesterase inhibitor therapy in older adults with major depression


Dr. Reynolds has financial interests with the following any entity or entities producing health care goods or services as indicated below:

Board Membership 

American Association of Geriatric Psychiatry  Editorial Review Board Fee
Extramural Support  (past three years to current)      
National Institute of Health (NIH)
National Institute of Mental health (NIMH)
National Institute on Aging (NIA)
National Center for Minority Health Disparities (NIMHD)
National Heart Lung and Blood Institute (NHLBI)
Center for Medicare and Medicaid Services (CMS)
Patient Centered Outcomes Research Institute (PCORI)
John A. Hartford Foundation
American Foundation for Suicide Prevention
Commonwealth of Pennsylvania
Clinical and Translational Science Institute (CTSI)
American Association for Geriatric Psychiatry (for my services as associate editor)
UPMC Endowment in Geriatric Psychiatry (which supports my endowed professorship).
Bristol Meyers Squibb, Forrest Labs, Lily, Pfizer provide pharmaceutical supplies for NIH-
sponsored work. 
(The pharmaceutical companies play no role in the design, analysis, or reporting of my data in
peer reviewed journals.)
Licensed Intellectual Property (co-inventor) 
Psychometric analysis of the Pittsburgh Sleep Quality Index (PSQI) 
PRO10050447 (PI:  Dr. Daniel Buysse)

The University of Pittsburgh School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. The University of Pittsburgh School of Medicine designates this educational activity for a maximum of 1.0 AMA PRA Category 1 CreditsTM. Each physician should only claim credit commensurate with the extent of their participation in the activity.

Release Date: 2/22/2011 | Last Modified On: 4/18/2011 | Expires: 4/18/2013

This course has been expired.