Linking Late-life Depression to Mild Cognitive Impairment and Future Dementia

UPMC psychiatrist, Dr. Charles Reynolds, discusses the link between late-life depression and future dementia in this recent presentation of the outcomes of the MTLD-III trial. This presentation was part of the speaker series presented by the Aging Institute of UPMC Senior Services and the University of Pittsburgh.

Learning Goals and Objective

After completing this course, participants will:

Specify the relationships between depression and dementia in older adults
Identify the clinical manifestations and significance of mild cognitive impairment in older adults with major depression
List the benefits and risks of adjunctive cholinesterase inhibitor therapy in older adults with major depression

Disclosures

Dr. Reynolds has financial interests with the following any entity or entities producing health care goods or services as indicated below:

Board Membership

American Association of Geriatric Psychiatry Editorial Review Board Fee

Extramural Support (past three years to current)
National Institute of Health (NIH)
National Institute of Mental health (NIMH)
National Institute on Aging (NIA)
National Center for Minority Health Disparities (NIMHD)
National Heart Lung and Blood Institute (NHLBI)
Center for Medicare and Medicaid Services (CMS)
Patient Centered Outcomes Research Institute (PCORI)
John A. Hartford Foundation
American Foundation for Suicide Prevention
Commonwealth of Pennsylvania
Clinical and Translational Science Institute (CTSI)
American Association for Geriatric Psychiatry (for my services as associate editor)
UPMC Endowment in Geriatric Psychiatry (which supports my endowed professorship).

Grant
Bristol Meyers Squibb, Forrest Labs, Lily, Pfizer provide pharmaceutical supplies for NIH-
sponsored work.
(The pharmaceutical companies play no role in the design, analysis, or reporting of my data in
peer reviewed journals.)

Licensed Intellectual Property (co-inventor)
Psychometric analysis of the Pittsburgh Sleep Quality Index (PSQI)
PRO10050447 (PI: Dr. Daniel Buysse)

The University of Pittsburgh School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. The University of Pittsburgh School of Medicine designates this educational activity for a maximum of 1.0 AMA PRA Category 1 Credits^TM. Each physician should only claim credit commensurate with the extent of their participation in the activity.

Release Date: 2/22/2011 | Last Modified On: 4/18/2011 | Expires: 4/18/2013

This course has been expired.

Presenters

Charles F. Reynolds III, MD

Charles F. Reynolds III, MD, is distinguished professor of psychiatry, neurology, behavioral and community Sciences, and clinical and translational science, and UPMC endowed professor in geriatric psychiatry. He is director of the Aging Institute of UPMC Senior Services and University of Pittsburgh, and the NIMH-sponsored Center of Excellence in the Prevention and Treatment of Late Life Mood Disorders, and the John A. Hartford Center of Excellence in Geriatric Psychiatry. Dr. Reynolds is internationally renowned in the field of geriatric psychiatry. His primary research interests focus on mood, grief, and sleep disorders of later life, with a particular focus on mental health services in primary care, improving treatment strategies, depression prevention, and promotion of brain health in older adults. He has served the Corbett administration as a member of the Pennsylvania Long-term Care Commission and the Pennsylvania Alzheimer?s Disease State Planning Committee. He also served on Governor Wolfe?s transition team for Aging. Dr. Reynolds? bibliography contains more than 700 publications in peer-reviewed journals with an H-Index of 81 (June 2016), which he has written over the past three decades. Dr. Reynolds is Editor-in-Chief of the American Journal of Geriatric Psychiatry, and has also served on the editorial board of the American Journal of Psychiatry and JAMA Psychiatry. He has published his work in the New England Journal of Medicine, JAMA, the Lancet, the British Medical Journal, the American Journal of Psychiatry, and the Archives of General Psychiatry. Dr. Reynolds graduated magna cum laude from the University of Virginia before earning his medical degree from Yale University School of Medicine in 1973. He then completed a straight medical internship at the Royal Victoria Hospital and Montreal Neurological Hospital and continued on to post-graduate work in adult and geriatric psychiatry and sleep disorders at the Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center.
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