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Dr. Robert Hendricks presents on reversible corneal nerve damage causes chronic immunopathology in murine herpes stromal keratitis and Dr. Deepinder Dhaliwal presents on Surgery in Patients with Ocular Herpes and Compromised Corneas. 

Educational objectives:

Upon completion of this activity, participants should be able to:

  • Review the use of steroids for patients with ocular herpes and compromised corneas
  • Discuss approach to cataract surgery ocular herpes and compromised corneas
  • Review mechanisms of pathology associated with herpes stromal keratitis (HSK)
  • Discuss the association of HSV-1 corneal infections and loss of sensory nerve endings and sensation in the cornea.

Reading Resources:

  1. Yun, H., A. M. Rowe, K. L. Lathrop, S. A. Harvey, and R. L. Hendricks. 2014. Reversible nerve damage and corneal pathology in murine herpes simplex stromal keratitis. J.Virol. 88:7870-7880. 
  2. Rowe, A. M., A. J. St Leger, S. Jeon, D. K. Dhaliwal, J. E. Knickelbein, and R. L. Hendricks. 2013. Herpes keratitis. Prog.Retin.Eye Res. 32:88-101. 
  3. Knickelbein, J. E., R. L. Hendricks, and P. Charukamnoetkanok. 2009. Management of herpes simplex virus stromal keratitis: an evidence-based review. Surv.Ophthalmol. 54:226-234. Knickelbein, J. E., K. M. Khanna, M. B. Yee, C. J. Baty, P. R. Kinchington, and R. L. Hendricks. 2008. Noncytotoxic lytic granule-mediated CD8+ T cell inhibition of HSV-1 reactivation from neuronal latency. Science 322:268-271. 

Disclosures:

Dr. Hendricks has reported no relevant relationships with any entities producing health care goods or services.

Dr. Dhaliwal has financial interests with the following any entity or entities producing health care goods or services as indicated below:

  • Grant/Research Support: AMO, Avedro, Eleven

Accreditation Statement:

The University of Pittsburgh School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The University of Pittsburgh School of Medicine designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credits™. Each physician should only claim credit commensurate with the extent of their participation in the activity. Other health care professionals are awarded (0.1) continuing education units (CEU) which are equivalent to 1.0 contact hour.

For your credit transcript, please access our website 4 weeks post-completion at http://ccehs.upmc.edu and follow the link to the Credit Transcript page. If you do not provide the last 5 digits of your SSN on the next page you will not be able to access a CME credit transcript. Providing your SSN is voluntary.

Release Date: 5/10/2014 | Last Modified On: 6/24/2014 | Expires: 6/24/2016

This course has been expired.