You are viewing the 1st of the 2 courses UPMC Physician Resources permits you to view without registering. To have full access to our FREE courses on our website, please register or log in now.

Dr. O'Keefe will discuss the critical role of the microbiota in mucosal health and colon cancer risk.

Educational objectives:

Upon completion of this activity, participants should be able to:

  • Counsel patients on how to reduce their risk of colon cancer
  • Describe the human microbiota
  • Describe gut physiology

Reading Resources:

  1. The microbiota and its metabolites in colonic mucosal health and cancer risk. Vipperla K, O'Keefe SJ. Nutr Clin Pract. 2012 Oct;27(5):624-35. doi: 10.1177/0884533612452012.
  2. Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour. Cryan JF, Dinan TG. Nat Rev Neurosci. 2012 Oct;13(10):701-12.
  3. Alterations in the intestinal microbiota promote colorectal cancer. Cancer Discov. 2012 Oct;2(10):866.


Dr. O'Keefe has no relevant relationships with any entities producing health care goods or services.

Accreditation Statement:

The University of Pittsburgh School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The University of Pittsburgh School of Medicine designates this enduring material for a maximum of 0.50 AMA PRA Category 1 CreditsTM. Each physician should only claim credit commensurate with the extent of their participation in the activity. Other health care professionals are awarded (0.05) continuing education units (CEU) which are equivalent to 0.50 contact hour.

For your credit transcript, please access our website 4 weeks post-completion at and follow the link to the Credit Transcript page. If you do not provide the last 5 digits of your SSN on the next page you will not be able to access a CME credit transcript. Providing your SSN is voluntary.

Release Date: 1/10/2013 | Last Modified On: 5/6/2014 | Expires: 5/6/2015

This course has been expired.