New Consensus Criteria on Renal Dysfunction in Critically Ill Children
March 21, 2022
In January 2022, the journal Pediatrics from the American Academy of Pediatrics published findings from the Pediatric Organ Dysfunction Information Update Mandate (PODIUM) Consensus Conference.
PODIUM sought to develop consensus criteria on organ dysfunction in critically ill children by evaluating the existing evidence base across the various organ systems and develop standardized metrics and qualifications for defining organ dysfunction that goes beyond the classical approach of expert opinion.
UPMC Children’s Division of Pediatric Nephrology faculty, Dana Y. Fuhrman, DO, MS, associate professor of Pediatrics and Critical Care Medicine was a member of the panel tasked with developing consensus criteria for classifying renal dysfunction in children experiencing a critical illness.1
Dr. Fuhrman’s clinical work and research as a pediatric nephrologist and critical care specialist is focused on acute kidney injury, renal reserve, and continuous renal replacement therapy.
The consensus criteria around renal dysfunction entails updated criteria for urine output and serum creatinine indications, estimated glomerular filtration rate levels, fluid overload, or the necessity for renal replacement therapy.
The panel examined more than 6,000 studies and supporting evidence in order to develop the consensus criteria.
The panel also developed criteria for classifying those increase risk for kidney dysfunction and for whom persistent renal dysfunction may be an outcome of their critical illness.
“These new criteria for establishing the presence of renal dysfunction in critically ill children will help to standardize diagnostic approaches and provide clearer indications for high-risk individuals and when long-term dysfunction may be a possibility,” says Dr. Fuhrman.
Read more about PODIUM and the consensus criteria on renal dysfunction using the reference below.
Reference
Fitzgerald JC, Basu RK, Fuhrman DY, Goga SM, Hassinger AB, Sanchez-Pinto N, Selewski DT, Sutherland SM, Akcan-Arikan A, on behalf of the Pediatric Organ Dysfunction Information Update Mandate (PODIUM) Collaborative. Renal Dysfunction Criteria in Critically Ill Children: The PODIUM Consensus Conference. Pediatrics. 2022; 149 (1 Suppl 1): S1-S12.
More About Dr. Fuhrman
Dana Y. Fuhrman, DO, MS, is an Associate Professor of Critical Care Medicine and Pediatrics at the University of Pittsburgh School of Medicine. She is an attending physician in the Division of Pediatric Nephrology at UPMC Children’s Hospital of Pittsburgh, and she also currently serves as the associate program director of the Pediatric Critical Care Medicine Fellowship.
Dr. Fuhrman’s research interests are in the areas of AKI and continuous renal replacement therapy. Currently, her research focus is in the prevention and early detection of AKI in children. She is interested in studying renal reserve as defined by the difference in a baseline and a protein stimulated glomerular filtration rate. Dr. Fuhrman’s work seeks to better understand how children with lower renal reserve values are at a greater risk for AKI after cardiac surgery. Her work also involves investigations of cell cycle arrest biomarkers, tissue inhibitor of metalloproteinases-2 and insulin-like growth factor binding protein 7, as a means to predict AKI risk and diagnosis the condition earlier.
Learn more about Dr. Fuhrman’s training and recent published research.
