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Researchers in the Renal-Electrolyte Division are engaged in a diverse array of basic science, translational, and clinical investigations on numerous aspects of kidney development and disease. Below is a selection of recent high-impact publications from faculty members.
Lakkis FG, Chalasani G, Hariharan S. Antibody-Mediated Rejection of Solid-Organ Allografts. N Engl J Med. 2018 Dec 27; 379(26): 2580.
Rondon-Berrios H, Tandukar S, Mor MK, Ray EC, Bender FH, Kleyman TR, Weisbord SD. Urea for the Treatment of Hyponatremia. Clin J Am Soc Nephrol. 2018 Nov 7; 13(11): 1627-1632.
Ray EC, Miller RG, Demko JE, Costacou T, Kinlough CL, Demko CL, Unruh ML, Orchard TJ, Kleyman TR. Urinary Plasmin(ogen) as a Prognostic Factor for Hypertension. Kidney Int Rep. 2018 Jun 30; 3(6): 1434-1442.
Jhamb M, Abdel-Kader K, Yabes J, Wang Y, Weisbord SD, Unruh M, Steel JL. Comparison of Fatigue, Pain and Depression in Patients With Advanced Kidney Disease and Cancer — Symptom Burden and Clusters. J Pain Symptom Manage. 2018 Dec 12. pii: S0885 3924(18)31120-5.
Boyd-Shiwarski CR, Shiwarski DJ, Roy A, Namboodiri HN, Nkashama LJ, Xie J, McClain KL, Marciszyn A, Kleyman TR, Tan RJ, Stolz DB, Puthenveedu MA, Huang C, Subramanya AR. Potassium-Regulated Distal Tubule WNK Bodies Are Kidney-Specific WNK1 Dependent. Mol Biol Cell. 2018 Feb 15; 29(4): 499-509.
Division News and Notes
Jane Schell, MD, was awarded the Hastings Center Cunniff-Dixon Foundation Early Career Award for her dedication to improving the care of seriously ill patients with kidney disease. The prestigious national award is given annually to five palliative care doctors whose work enriches the relationship of doctors and their patients who are near the end of life. Dr. Schell developed NephroTalk, a nationally recognized curriculum that prepares nephrology fellows to have difficult conversations with patients and families, including end-of-life discussions. She is an associate professor in the Divisions of Renal-Electrolyte and General Internal Medicine.
Notable New Grants
Manisha Jhamb, MD, MPH, and Khaled Abdel-Kader, MD, MS (Vanderbilt Center for Kidney Disease),
Population Health Management to Optimize Care for Patients with High Risk Chronic Kidney Disease. NIDDK R01 DK116957
Manisha Jhamb, MD, MPH,
OPTIMIZing carE in Chronic Kidney Disease (OPTIMIZE CKD). NIDDK R18 DK118460
Lori Birder, PhD, and Gerard Apodaca, PhD,
Bladder Mucosal Dysfunction During Aging. NIA R01 AG056944
Thomas Kleyman, MD,
Pittsburgh Center for Kidney Research. NIDDK P30 DK079307
Thomas Kleyman, MD,
Renal and Epithelial Biology Training Program. NIDDK T32 DK061296
Cary Boyd-Shiwarski, MD, PhD
The Function of Kidney Specific (KS)-WNK1 Condensates During Potassium Stress. NIDDK K08 DK118211
Roderick Tan, MD, PhD
Tubular to Glomerular Crosstalk in Proteinuric Chronic Kidney Disease. American Society of Nephrology (ASN) Carl W. Gottschalk Research Scholar Grant