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Researchers Present at the 2018 American Association for Cancer Research (AACR) Annual Meeting

April 13, 2018

Cancer scientists and physicians of UPMC Hillman Cancer Center, affiliated with the University of Pittsburgh School of Medicine, , will share their latest research breakthroughs at the American Association for Cancer Research (AACR) Annual Meeting in Chicago April 14 to 18. Below is a collection of some of these presentations:

Saturday, April 14

Room W196, McCormick Place West (Level 1)
Tumor Immunology and Immunotherapy for Nonimmunologists: Roundtable Discussions
Chair: Olivera J. Finn, Pittsburgh, PA
Human immune monitoring and biomarkers. Lisa H. Butterfield, Pittsburgh, PA
Topic to be announced. Olivera J. Finn, Pittsburgh, PA
Topic to be announced. Theresa L. Whiteside, Pittsburgh, PA

Room S406 (Vista Ballroom), McCormick Place South (Level 4)
Methods to Evaluate the Immunologic Landscape of Tumors Chair:
Measuring effector and suppressor cellular responses and circulating proteins. Lisa H. Butterfield, Pittsburgh, PA

Room S105, McCormick Place South (Level 1)
New Developments in the Treatment of Metastatic Colorectal Cancer
Chair: Edward Chu, Pittsburgh, PA
3:15 p.m. Overview on the treatment of metastatic colorectal cancer. Edward Chu, Pittsburgh, PA
4:45 p.m. Title to be announced. James J. Lee, Pittsburgh, PA

Sunday, April 15

Room S501, McCormick Place South (Level 5) Clinical Research Radiation Science
3:35 p.m. 980 Molecular basis of adipose-derived stem cell (ASCs) therapy for management of radiation-induced fibrosis (RIF). Asim Ejaz, Pittsburgh, PA

Monday, April 16

Room S105, McCormick Place South (Level 1)
Digital Pathology: Advances in Cancer Diagnostics
1:35 p.m. Telepathology: The value of internal and international teleconsultation for cancer diagnostics. Liron Pantanowitz, Pittsburgh, PA

Room S504, McCormick Place South (Level 5)
Cutting-Edge Head and Neck Cancer Therapy
1:30 p.m. Multimodality precision immunotherapy. Umamaheswar Duvvuri, Pittsburgh, PA; J. Silvio Gutkind, La Jolla, CA

Clinical Trials Minisymposium 2; 3 to 5 p.m.

N Hall C, McCormick Place North (Level 1) Updates in Immuno-oncology Trials
4:35 p.m. CT116 Nivolumab (Nivo) vs investigator’s choice (IC) in recurrent or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN): 2-yr outcomes in the overall population and PD-L1 subgroups of CheckMate 141. Robert L. Ferris, Pittsburgh, PA

Tuesday, April 17

Recent Advances in Prevention and Interception Research 10:30 a.m. to 12:15 p.m.

Room W196, McCormick Place West (Level 1) Cancer Vaccines and Prevention
Chair: Olivera J. Finn, Pittsburgh, PA
11:30 a.m. Targeting premalignant lesions with a MUC1 peptide vaccine. Olivera J. Finn, Pittsburgh, PA

Room S406 (Vista Ballroom), McCormick Place South (Level 4) Integrative Data Science for the Precision Medicine Era
2:05 p.m. Towards a pathology imaging data commons for discovery and precision oncology. Michael J. Becich, Pittsburgh, PA

Clinical Trials Minisymposium 3; 2:45 to 5 p.m.

N Hall C, McCormick Place North (Level 1) Biomarkers in Immuno-oncology
3:05 p.m. CT176 Effect of JAK/STAT or PI3Kδ plus PD-1 inhibition on the tumor microenvironment: Biomarker results from a phase Ib study in patients with advanced solid tumors. John M. Kirkwood, Pittsburgh, PA

Room S505, McCormick Place South (Level 5)
Prevention Research Preclinical Studies of Cancer Prevention
Cochairs: Zigang Dong, Austin, MN; Shivendra V. Singh, Pittsburgh, PA

Recent Advances in Diagnostics and Therapeutics Research 10:15 a.m. to 12:00 p.m.

Room S404, McCormick Place South (Level 4) FGFR Signaling in Cancer
Chair: Steffi Oesterreich, Pittsburgh, PA
10:45 a.m. FGFR4—a new druggable target in endocrine resistant breast cancer. Steffi Oesterreich, Pittsburgh, PA

2018 AACR-Get Your Rear in Gear Philadelphia Scholar in Training Awards Supported by the Colon Cancer Coalition

Get Your Rear in Gear Philadelphia has graciously donated funds to the AACR to support early-career investigators who will be presenting meritorious abstracts on colorectal cancer research at the AACR Annual Meeting 2018.

  • Rochelle E. Fletcher, BA, University of Pittsburgh School of Medicine, Pittsburgh, PA. Abstract 267. Nonsteroidal anti-inflammatory drugs induce ER stress- and BID-dependent immunogenic cell death to suppress colorectal tumorigenesis