New Study Explores Medication-Induced Pericarditis and Myocarditis in Pediatric Inflammatory Bowel Disease

July 25, 2022

A team from the Division of Gastroenterology, Hepatology and Nutrition and the Heart Institute at UPMC Children’s Hospital of Pittsburgh published a new article in the journal Cureus that explores the development of medication-induced myocarditis and pericarditis in pediatric patients with inflammatory bowel disease (IBD).

Myocarditis and pericarditis are among a large, yet rare group of extraintestinal complications that can affect many organs throughout the body and can lead to significant morbidities and decreases in quality of life.

Lead author of the study was former GI fellow Kevin Cesa, MD. Also contributing to the research were University of Pittsburgh School of Medicine student Catherine Cunningham, Tyler Harris, MD, assistant professor of pediatrics and associate director of the Pediatric Cardiology Fellowship Program in the Heart Institute at UPMC Children’s, and senior author, Whitney Sunseri, MD, assistant professor of Pediatrics in the Division of Pediatric Gastroenterology, Hepatology, and Nutrition at UPMC Children’s and assistant program director for the Division’s Fellowship Program.

In the article, titled “A Review of Extraintestinal Manifestations and Medication-Induced Myocarditis and Pericarditis in Pediatric Inflammatory Bowel Disease,” the team explores the effects IBD has on organs throughout the body, and in particular, the heart. While rare, these extraintestinal symptoms within the heart are associated with significant morbidity.

The study reviewed the existing literature on the prevalence and etiology of pericarditis and myocarditis in the setting of IBD with the twin goals of helping clinicians identify and treat the disorders and providing a critical review of gaps in understanding and research that could in the future work to expand the evidence surrounding these rare complications induced by IBD in pediatric patients.

Read the paper in its entirely using the reference and link below.

Learn more about the Division of Pediatric Gastroenterology, Hepatology and Nutrition and the Heart Institute at UPMC Children’s Hospital of Pittsburgh.

Reference

Cesa K, Cunningham C, Harris T, Sunseri W. A Review of Extraintestinal Manifestations & Medication-Induced Myocarditis and Pericarditis in Pediatric Inflammatory Bowel Disease. Cureus. June 27, 2022; 14(6): e26366.