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José-Alain Sahel, MD, was the keynote speaker at the 33rd Biennial Center for Visual Science Symposium at the University of Rochester. He recently joined John Foxe, PhD, for a "Neuroscience Perspectives" podcast episode to discuss his gene therapy research and clinical trial efforts.
Dr. Sahel is a distinguished professor and chair of the Department of Ophthalmology at the University of Pittsburgh School of Medicine and the endowed chair of the Eye & Ear Foundation. He is also the director of the UPMC Vision Institute.
Dr. Sahel is a leading expert in retinal diseases and vision restoration research and is a pioneer in optogenetic vision restoration. This therapeutic technique uses genetically modified cells in the retina to express light-sensitive proteins and could help patients who are blind or visually impaired because of a genetic defect. His research has also helped to develop several other interventions for vision impairment including stem cell implantation, gene therapy, innovative pharmacologic approaches, and the artificial retina.