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UPMC Physicians and Researchers Present at the American Heart Association (AHA) Scientific Sessions 2018

November 1, 2018 UPMC, the University of Pittsburgh, and UPMC Children’s Hospital of Pittsburgh will be well-represented at the AHA Scientific Sessions 2018, held November 10-12 in Chicago, IL. Physicians and researchers will join colleagues from around the country to discuss advancements in clinical practice and research, including focuses on cutting-edge prevention and digital healthcare solutions. 

AHA Scientific Sessions 2018 UPMC Presentations 

November 10, 2018

Sa3092/3092 - High incidence of Congenital Heart Defects in a Dominant Mouse Forward Genetic Screen Using Fetal Echocardiography 
Authors: Tuantuan Tan, Michael Wang, Caleb W Radomile, Sebastian Elliot Ho, Devine William, Xiaoqin Liu, UPMC, PGH, PA; Reinholdt Laura, The Jackson Lab, Bar Harbor, MA; Yijen Wu, Lauren Elizabeth Meyer, Cecilia W Lo, UPMC, Pittsburgh, PA

Sa4122/4122 - Targeted Cardiac Delivery of miR-29b Mimic via Ultrasound-Mediated Microbubble Cavitation Attenuates Myocardial Fibrosis 
Authors: Rafey A Feroze, UPMC, Pittsburgh, PA; Jonathan Kopechek, Univ of Louisville, Louisville, KY; Linda Lavery, Jissy Cyriac, Jianhui Zhu, Xucai Chen, Flordeliza Villanueva, UPMC, Pittsburgh, PA

249 - Primary Presentation of Pulmonary Hypertension in the Peripartum: Preparing for Patients With Eisenmenger's Physiology 
Authors: Malamo E Countouris, Arun Jeyabalan, John Caldwell, Jenifer Lee, Gavin Hickey, UPMC, Pittsburgh, PA

ISC02/209 - Eligibility for Endovascular Trial Enrollment in the 6-24 Hour Time Window: Analysis of a Single Comprehensive Stroke Center 
Authors: Shashvat M Desai, Ashutosh P Jadhav, Tudor G Jovin, UPMC Stroke Institute, Pittsburgh, PA

Sa3126/3126 - Characterization of Neurodevelopmental Defects Associated With a Mouse Model of Hypoplastic Left Heart Syndrome 
Authors: George C Gabriel, Nathan Salamacha, University of Pittsburgh School of Med, Pittsburgh, PA; William T Reynolds, Children's Hosp of Pittsburgh of UPMC, Pittsburgh, PA; Tuantuan Tan, Xiaoqin Liu, Hisato Yagi, Abha Bais, University of Pittsburgh Sch of Med, Pittsburgh, PA; Ashok Panigrahy, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA; Dennis Simon, Yijen Wu, Cecilia W Lo, University of Pittsburgh School of Med, Pittsburgh, PA

 Sa1319/1319 - Real-World Direct Comparison of the Effectiveness and Safety of Apixaban, Dabigatran, Rivaroxaban, and Warfarin in Medicare Beneficiaries With Fibrillation: A Subgroup Analyses by a History of Ischemic Stroke
Authors: Lanting Yang, University of Pittsburgh, Pittsburgh, PA; Samir Saba, UPMC, Pittsburgh, PA; Yuting Zhang, Inmaculada Hernandez, University of Pittsburgh, Pittsburgh, PA

Aortic Prosthetic Valve Stenosis (Low Risk 60 yo. Patient): TAVR v-in-v vs. Redo AVR (Redo AVR Approach)
Author: Thomas Gleason, Pittsburgh, PA


318 - Bola3 Deficiency Controls Endothelial Metabolism and Glycine Homeostasis in Pulmonary Hypertension 
Authors: Qiujun Yu, Yi-Yin Tai, Ying Tang, Jingsi Zhao, Univ of Pittsburgh, Pittsburgh, PA; Thomas Bertero, Univ of Nice Sophia Antipolis, Medical Sch, Nice, France; Vinny Negi, Miranda K Culley, University of Pittsburgh, Pittsburgh, PA; Rajeev Saggar, Univ of Arizona, Phoenix, AZ; Rajan Saggar, W. Dean Wallace, David J Ross, David Geffen Sch of Med, Univ of California, Los Angeles, CA; Aaron B Waxman, Brigham and Women’s Hosp, Harvard Medical Sch, Boston, MA; Stacy G Wendell, Steven J Mullett, University of Pittsburgh, Pittsburgh, PA; Omar F Khan, Massachusetts Inst of Technology, Cambridge, MA; James Dahlman, Georgia Inst of Technology, Atlanta, GA; John Gorcsan III, Washington Univ in St. Louis, St. Louis, MO; Sara O Vargas, Boston Children’s Hosp, Boston, MA; Kathleen J Haley, Brigham and Women’s Hosp, Harvard Medical Sch, Boston, MA; Rahul Kumar, Brian B Graham, Univ of Colorado, Denver, CO; Robert Langer, Daniel G Anderson, Massachusetts Inst of Technology, Cambridge, MA; Bing Wang, University of Pittsburgh School of Med, Pittsburgh, PA; Sruti Shiva, Stephen Y Chan, University of Pittsburgh, Pittsburgh, PA

Sa3126/3126 - Characterization of Neurodevelopmental Defects Associated With a Mouse Model of Hypoplastic Left Heart Syndrome 
Authors: George C Gabriel, Nathan Salamacha, University of Pittsburgh School of Medicine, Pittsburgh, PA; William T Reynolds, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA; Tuantuan Tan, Xiaoqin Liu, Hisato Yagi, Abha Bais, University of Pittsburgh School of Med, Pittsburgh, PA; Ashok Panigrahy, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA; Dennis Simon, Yijen Wu, Cecilia W Lo, University of Pittsburgh School of Medicine, Pittsburgh, PA

460 - Obstetric and Cardiovascular Outcomes in Pregnant Women With Hypertrophic Cardiomyopathy: A Nationwide Cohort Study and a Propensity Score-Matched Analysis 
Authors: Ahmad Masri, University of Pittsburgh Medical Center, Pittsburgh, PA; Karam Ayoub, Univ of Kentucky, Lexington, KY; Meera Marji, Univ of Kentucky, Kentucky, KY; Moaz Baghal, Ahmad Altibi, Jenna Skowronski, Malamo Countouris, Michael Genuardi, Kathryn Berlacher, Steve Caritis, University of Pittsburgh Medical Center, Pittsburgh, PA; Steven Reis, University of Pittsburgh, Pittsburgh, PA; Timothy Wong, University of Pittsburgh Medical Center, Pittsburgh, PA

SaMDP29 - Pregnancy-Related Events Associated With Subclinical Cardiovascular Disease Burden in Late Midlife: SWAN 
Authors: Yamnia I Cortes, Univ of North Carolina at Chapel Hill, Chapel Hill, NC; Maria Brooks, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA; Janet M Catov, University of Pittsburgh and Magee-Women's Res Insitute, Pittsburgh, PA; Samar R El Khoudary, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA; Rebecca C. Thurston, Karen A Matthews, University of Pittsburgh School of Med, Pittsburgh, PA; Carmen R Isasi, Albert Einstein Coll of Med, Bronx, NY; Elizabeth A Jackson, Univ of Alabama at Birmingham Sch of Med, Birmingham, AL; Emma Barinas-Mitchell, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA

SaMDP35 - Communication in Pediatric Cardiac Intensive Care Unit Family Meetings May Benefit From Better Coordination of Team Members to Meet Family Needs 
Authors: Jennifer Walter, Theodore Schall, Aaron Dewitt, Children's Hosp of Philadelphia, Philadelphia, PA; Robert Arnold, University of Pittsburgh Medical Center, Pittsburgh, PA; Chris Feudtner, Children's Hosp of Philadelphia, Philadelphia, PA

Sa3087/3087 - Airway Mucociliary Clearance is Impaired After Infant Congenital Cardiac Surgery 
Authors: Phillip S Adams, Timothy Corcoran, Michael Czachowski, Al Saville, Ivy Lin, Yuliya Domnina, Tracy Baust, Omar Khalifa, Maliha Zahid, Joan Sanchez de Toledo, Cecilia W Lo, University of Pittsburgh School of Med, Pittsburgh, PA

Sa4256/4256 - Cardiac Targeting Peptide, a Novel Cardiac Vector: Studies in Biodistribution, Mechanisms of Transduction and Imaging Application
Authors: Maliha Zahid, Kyle Feldman, Timothy N. Feinstein, Nicholas Pogodzinski, Xinxiu Xu, Raymond Yurko, Michael R Czachowski, Yijen Wu, Cecilia W. Lo, Neal S. Mason, University of Pittsburgh, Pittsburgh, PA

 Sa3123/3123 - Waitlist Characteristics and Outcomes Following the 2016 Revision of US Pediatric Heart Allocation Policy 
Authors: Defne A. Magnetta, UPMC Children's Hosppital of Pittsburgh, Pittsburgh, PA; Justin Godown, Vanderbilt Univ Medical Ctr, Nashville, TN; Shawn West, Matthew Zinn, Susan Miller, Brian Feingold, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA

Sa2217/2217 - Acute Hemodynamic Effects of Oral Nitrite in Pulmonary Hypertension Related to Heart Failure With Preserved Ejection Fraction (PH-HFpEF)
Authors: Andrea R Levine, Nicole L Helbling, Nydia Chien, Timothy N Bachman, Marc A Simon, University of Pittsburgh, Pittsburgh, PA

Sa1319/1319 - Real-World Direct Comparison of the Effectiveness and Safety of Apixaban, Dabigatran, Rivaroxaban, and Warfarin in Medicare Beneficiaries With Fibrillation: A Subgroup Analyses by a History of Ischemic Stroke 
Authors: Lanting Yang, University of Pittsburgh, Pittsburgh, PA; Samir Saba, UPMC, Pittsburgh, PA; Yuting Zhang, Inmaculada Hernandez, Univ of Pittsburgh, Pittsburgh, PA

 Sa2461/2461 - Identifying Temporal Relationships Between Adverse Events Following Implantation of Durable Left Ventricular Assist Devices 
Authors: Arman Kilic, University of Pittsburgh, Pittsburgh, PA; Francis D Pagani, Donald S Likosky, Univ of Michigan, Ann Arbor, MI; Laura M Seese, Andrew D Althouse, Robert L Kormos, University of Pittsburgh, Pittsburgh, PA

Sa2394/2394 - Temporal Patterns of Self-Weighing Behavior and Weight Loss in the Health eHeart Study
Authors: Yaguang Zheng, University of Pittsburgh, Pittsburgh, PA; Geoffrey H. Tison, Univ of California, San Francisco, San Francisco, CA; Susan M. Sereika, Lora E. Burke 15213, University of Pittsburgh, Pittsburgh, PA; Jeffrey Olgin, Gregory M. Marcus, Kirstin Aschbacher, Mark J. Pletcher, Univ of California, San Francisco, San Francisco, CA

368 - Surgery for Type A Aortic Dissection in Patients With Cerebral Malperfusion. Results From the International Registry of Aortic Dissections 
Authors: Ibrahim Sultan, University of Pittsburgh, Pittsburgh, PA; Himanshu Patel, Univ of Michigan, Ann Arbor, MI; Marco Di Eusanio, Politecnica Univ of Marche, Ancona, Italy; Ed Chen, Bradley Leshnower, Emory Univ, Atlanta, GA; George Arnaoutakis, Univ of Florida, Gainesville, FL; Joseph Bavaria, U of Pennsylvania, Philadelphia, PA; Derek Brinster, Northwell, New York, NY; Thor Sundt, MGH, Boston, MA; Davide Pacini, S. Orsola-Malpighi Hosp, Bologna, Italy; Udo Sechtem, Robert Bosch Hosp, Stuttgart, Germany; Anil Bhan, Mediciti, Mediciti, India; Daniel Montgomery, Univ of Michigan, Ann Arbor, MI; Truls Myrmel, U of Norway, Norway, Norway; Santi Trimarchi, IRCCS Policlinico San Donato, Cardiovascular Ctr, Pittsburgh, Italy; Kim Eagle, U of Michigan, Ann Arbor, MI; Thomas Gleason, University of Pittsburgh, Pittsburgh, PA

Sa2399/2399 - Geospatial Analysis of Chest Pain Patients That Call 9-1-1
Authors: Stephanie O. Frisch, University of Pittsburgh, Pittsburgh, PA; Mohammad Alrawashdeh, Jordan Univ Of Science and Technology, Ar Ramtha, Jordan; Christian Martin-Gill, Clifton Callaway, University of Pittsburgh Medical Center, Pittsburgh, PA; Salah Al-Zaiti, University of Pittsburgh, Pittsburgh, PA

Sa2434/2434 - Oxidative Stress Induced Calpain and Caspase-3 is Increased in Aortic Smooth Muscle Cells Derived From Bicuspid Aortic Valve Patients 
Authors: Patrick G. Chan, Julie A. Phillippi, Marie Billaud, Thomas G. Gleason, University of Pittsburgh, Pittsburgh, PA

HTN17/176 - Neurons in the Organum Vasculosum of the Lamina Terminalis Sense NaCl and Angiotensin II to Regulate Sympathetic Nerve Activity and Arterial Blood Pressure
Authors: Sean D Stocker, Brian J Kinsman, Kirsteen N Browning, University of Pittsburgh, Pittsburgh, PA; Megan M Wenner, William B Farquhar, Univ of Delaware, Newark, DE

272 - Tissue Plasminogen Activator Loaded Microbubbles for the Treatment of Coronary Microvascular Obstruction 
Authors: Stephen J D'Auria, Filip Istvanic, Francois Yu, University of Pittsburgh Medical Center, Pittsburgh, PA; Xucai Chen, University of Pittsburgh, Pittsburgh, PA; John Pacella, University of Pittsburgh Medical Center, Pittsburgh, PA

 Sa1095/1095 - Change in Galectin-3 Levels and Incidence of Cardiovascular Disease: Insights From the Atherosclerosis Risk in Communities Study 
Authors: Anum Saeed, University of Pittsburgh, Pittsburgh, PA; David Aguilar, Univ of Texas Health Science Ctr Houston, Houston, TX; Wensheng Sun, Ron Hoogeveen, Vijay Nambi, Baylor Coll of Med, Houston, TX; Elizabeth Selvin, Kunihiro Matsushita, Johns Hopkins Bloomberg Sch of Public Health, Baltimore, MD; John McEvoy, Johns Hopkins Univ Sch of Med, Baltimore, MD; Amil Shah, Brigham and Women's Hosp, Boston, MA; Scott D Solomon, Brigham and Women’s Hosp, Harvard Medical Sch, Boston, MA; Eric Boerwinkle, Univ of Texas Health Science Ctr Houston, Houston, TX; Christie M Ballantyne, Baylor Coll of Med, Houston, TX

 Sa4210/4210 - Diagnostic Accuracy of Dobutamine Stress Echocardiography in the Detection of Cardiac Allograft Vasculopathy in Heart Transplant Recipients: A Systematic Review and Meta-Analysis Study
Authors: Ahmed Elkaryoni, Univ of Missouri Kansas City, Kansas City, MO; Ahmed M.A. Altibi, University of Pittsburgh Medical Center, Pittsburgh, PA; Adil Hassan, Univ of Missouri Kansas City, Kansas City, MO; Ahmed Elgebaly, Faculty eof Med, Al-Azhar Univ, Cairo, Egypt; Eman M Elsabbagh, Univ of Chicago, Chicago, IL; Navin C. Nanda, Univ of Alabama at Birmingham, Birmingham, AL

Sa4122/4122 - Targeted Cardiac Delivery of miR-29b Mimic via ultrasound-Mediated Microbubble Cavitation Attenuates Myocardial Fibrosis 
Authors: Rafey A Feroze, UPMC, Pittsburgh, PA; Jonathan Kopechek, Univ of Louisville, Louisville, KY; Linda Lavery, Jissy Cyriac, Jianhui Zhu, Xucai Chen, Flordeliza Villanueva, UPMC, Pittsburgh, PA

Pregnancy as a Window Onto Future Cardiovascular Health 
Author: Janet M. Catov, Pittsburgh, PA 

Do Wearable Fitness Sleep Trackers Actually Work? Assessing Measurement Error and Validity Issues 
Author: Christopher E. Kline, Pittsburgh, PA 

249 - Primary Presentation of Pulmonary Hypertension in the Peripartum: Preparing for Patients With Eisenmenger's Physiology 
Authors: Malamo E Countouris, Arun Jeyabalan, John Caldwell, Jenifer Lee, Gavin Hickey, UPMC, Pittsburgh, PA

Sa4036/4036 - Regulation of Cell Proliferation in Renal Injury by Dopamine D2 Receptors
Authors: Megha Kumar, Laureano Asico, Prasad Konkalmatt, George Washington University, Washington, DC; Zachary Freyberg, University of Pittsburgh, Pittsburgh, PA; Pedro A Jose, George Washington Univ, Washington, DC; Ines Armando, George Washington University, Washington, DC

Aortic Prosthetic Valve Stenosis (Low Risk 60 yo Patient): TAVR v-in-v vs. Redo AVR (Redo AVR Approach) 
Author: Thomas Gleason, Pittsburgh, PA 

November 11, 2018

Su1185/1185 - Atrial Fibrillation Outcomes and Sex in a Tertiary Care Center, 2006-2017: The Burden in on Women
Authors: Zachary J. Rhinehart, Melissa Saul, Jared W. Magnani, UPMC, Pittsburgh, PA

Su1149/1149 - Relation of Income and Adverse Outcomes in Atrial Fibrillation: A Nationwide Health Claims Analysis 
Authors: Anna R LaRosa, University of Pittsburgh Medical Ctr, Pittsburgh, PA; J’Neka S. Claxton, Rollins Sch of Public Health, Emory Univ, Atlanta, GA; Wesley T. O'Neal, Sch of Med, Emory Univ, Atlanta, GA; Pamela L. Lutsey, Richard F. MacLehose, Sch of Public Health, Univ of Minnesota, Minneapolis, MN; Lin Y. Chen, Univ of Minnesota Medical Sch, Minneapolis, MN; Lindsay G.S. Bengtson, Life Sciences, Optum, Eden Prairie, MN; Alanna M. Chamberlain, Mayo Clinic, Rochester, MN; Alvaro Alonso, Rollins Sch of Public Health, Emory Univ, Atlanta, GA; Jared W. Magnani, UPMC Heart and Vascular Insitute, University of Pittsburgh, Pittsburgh, PA

Operative Strategies When PIT in Descending Aorta (Retrograde Type A): Total Arch and FET 
Author: Thomas Gleason, Pittsburgh, PA 

Su3045/3045 - Obesity Severity and Clinical Outcomes in Atrial Fibrillation 
Authors: Dingxin Qin, Michael Sharbaugh, Floyd Thoma, Andrew D Althouse, Stephen Koscumb, Amanda Malecky, Oscar Marroquin, Samir Saba, Erin E Kershaw, Suresh Mulukutla, Joao Cavalcante, University of Pittsburgh Med Center, Pittsburgh, PA

Su1352/1352 - Obstetric and Cardiovascular Outcomes in Pregnant Women With Left Ventricular Hypertrophy: A Nationwide Cohort Study and a Propensity Score-Matched Analysis 
Authors: Ahmad Masri, University of Pittsburgh Medical Center, Pittsburgh, PA; Karam Ayoub, Meera Marji, Univ of Kentucky, Lexington, KY; Moaz Baghal, Ahmed Altibi, Jenna Skowronski, Malamo Countouris, Michael Genuardi, Steve Caritis, Kathryn Berlacher, Univ of Pittsburgh Medical Ctr, Pittsburgh, PA; Steven Reis, University of Pittsburgh, Pittsburgh, PA; Timothy Wong, University of Pittsburgh Medical Center, Pittsburgh, PA

Su3045/3045 - Obesity Severity and Clinical Outcomes in Atrial Fibrillation 
Authors: Dingxin Qin, Michael Sharbaugh, Floyd Thoma, Andrew D Althouse, Stephen Koscumb, Amanda Malecky, Oscar Marroquin, Samir Saba, Erin E Kershaw, Suresh Mulukutla, Joao Cavalcante, University of Pittsburgh Med Center, Pittsburgh, PA

Su4191/4191 - Frataxin Deficiency Induces Endothelial Replication Stress and DNA Damage to Promote Pulmonary Hypertension 
Authors: Miranda Kay Culley, Jingsi Zhao, Ying Tang, Vinny Negi, Qiujun Yu, Yi Yin Tai, Adam Handen, University of Pittsburgh SOM, Pittsburgh, PA; Gil Speyer, Arizona State Univ, Tempe, AZ; Seungchan Kim, Prairie View A&M Univ, Prairie View, TX; Mingxia Gu, Marlene Rabinovitch, Stanford Univ, Stanford, CA; Dror Perk, Stephen Y Chan, University of Pittsburgh SOM, Pittsburgh, PA

494 - Pulmonary Vascular Endothelial Uptake of Blood-Borne microRNA-210 Contributes to the Development of Pulmonary Hypertension 
Authors: Jingsi Zhao, Yi-Yin Tai, Jonathan Florentin, University of Pittsburgh, Pittsburgh, PA; Thomas Bertero, Univ of Nice Sophia Antipolis, Nice, France; Vinny Negi, Ying Tang, Partha Dutta, Stephen Y. Chan, University of Pittsburgh, Pittsburgh, PA

Su1155/1155 - Correlation Between Vascular Aging and Functional Decline in Exceptionally Long-Lived Families 
Authors: Allison L Kuipers, Ryan L Minster, Emma Jm Barinas-Mitchell, University of Pittsburgh, Pittsburgh, PA; Kaare Cristensen, Danish Aging Res Ctr, Odense C, Denmark; Mary Feitosa, Washington Univ of St. Louis, St. Louis, MO; Stephani Cosentino, Columbia Univ, New York, NY; Stacy L Andersen-Toomey, Boston Univ Sch of Med, Boston, MA; Anne B Newman, University of Pittsburgh, Pittsburgh, PA; On behalf of the Long Life Family Study

Su1365/1365 - Women With Atrial Fibrillation Have Lower Quality of Life
Authors: Emily N Guhl, Andrew Althouse, Michael Sharbaugh, Alexandra Pusateri, Jared W Magnani, University of Pittsburgh, Pittsburgh, PA

Su1368/1368 - Follow-Up for Cardiovascular Disease Risk in Women With Preeclampsia One Year After Delivery 
Authors: Jenny Huang, Duane Eisaman, Kathryn Berlacher, Joe Suyama, University of Pittsburgh School of Medicine, Pittsburgh, PA

Su1007/1007 - Markers of Myocardial Injury and Strain Predict Microvascular Disease in Patients With Type 2 Diabetes Mellitus 
Author: Brendan M Everett, Brigham Womens Hosp, Boston, MA; Helen E.A. Vlachos, University of Pittsburgh, Pittsburgh, PA; Robert L. Frye, Mayo Clinic, Rochester, MN; Maria M Brooks, University of Pittsburgh, Pittsburgh, PA; Deepak L Bhatt, Brigham Womens Hosp, Boston, MA

Su3032/3032 - Thrombus Risk Prediction in Atrial Fibrillation: Hemodynamic Model of Left Atrial Appendage
Authors: Soroosh Sanatkhani, Prahlad G Menon, Sanjeev G Shroff, University of Pittsburgh, Pittsburgh, PA; Sotirios Nedios, Massachusetts General Hosp, Boston, MA

Su3033/3033 - Ventricular Tachycardia (VT) Increases Mortality in Atrial Fibrillation (AF): A Nationwide Study Using the National Inpatient Sample (NIS) 1999-2014
Authors: Rishi Shrivastav, Mount Sinai St. Luke’s Roosevelt Hos, New York, NY; Prateeth Pati, University of Pittsburgh, Pittsburgh, PA; Stuthi Perimbeti, Ashish Correa, Emad Aziz, Mount Sinai St. Luke’s Roosevelt Hos, New York, NY

Su4070/4070 - Predictors of VT <220 Bpm vs. VT/VF >_220 bmp in Raid Trial Patients
Authors: Alaa Shalaby, University of Pittsburgh/VA Pittsburgh Healthcare System, Pittsburgh, PA; David T Huang, Scott McNitt, Valentina Kutyifa, Univ of Rochester Medical Ctr, Rochester, NY; Abrar Shah, Rochester Univ Medical Ctr, Rochester, NY; James Daubert, Duke Univ Medical Ctr, Durham, NC; Wojciech Zareba, Rochester Univ Medical Ctr, Rochester, NY

Su4001/4001 - Right Bundle Branch Block (RBBB) is Associated With Poor Prognosis in Patients With Anterior Wall ST Elevation Myocardial Infarction (AWMI): A Nationwide Study Using the National Inpatient Sample (NIS) 
Authors: Rishi Shrivastav, Mount Sinai St. Luke’s Roosevelt Hos, New York, NY; Prateeth Pati, University of Pittsburgh, Pittsburgh, PA; Stuthi Perimbeti, Jacqueline Tamis-holland, Mount Sinai St. Luke’s Roosevelt Hos, New York, NY

Extracellular Matrix Stiffening Promotes Pulmonary Vascular Remodeling Through YAP/TAZ Dependent Mechanisms 
Author: Stephen Y. Chan, Pittsburgh, PA 

Heart Failure in African Americans: Exploring the potential mechanism (s) behind the enhanced response to Fixed dose Isordil/Hydralazine 
Author: Dennis McNamara, Pittsburgh, PA 

Heart Failure in the Elderly: the impact of cognition and frailty on heart failure care
Author: Daniel E. Forman, Pittsburgh, PA 

M.A.P. ping out BP Improvement in the Clinic: Progress towards Improvement 
Author: Sean D. Stocker, Pittsburgh, PA 

Invasive Assessment of RV Function: the role of RV/PA Coupling
Author: Marc Simon, Pittsburgh, PA 

Operative Strategies When PIT in Descending Aorta (Retrograde Type A): Total Arch and FET 
Author: Thomas Gleason, Pittsburgh, PA 

November 12, 2018

Mo4189/4189 - adipose Derived Stem Cells Enhance Cardiac Function Preservation of a Biodegradable Cardiac Patch and Increase Vascularization in Rats With Subacute Myocardial Infarction 
Authors: Noriyuki Kashiyama, Robert L Kormos, McGowan Inst for Regenerative Med, Univ of Pittsburgh the Heart and Vascular Inst, University of Pittsburgh Medical Center, Pittsburgh, PA; Yasumoto Matsumura, McGowan Inst for Regenerative Med, University of Pittsburgh, Pittsburgh, PA; Shin-ichi Higuchi, Lindemberg M Silveira-Filho, Garrett Coyan, McGowan Inst for Regenerative Med, University of Pittsburgh the Heart and Vascular Inst, University of Pittsburgh Medical Center, Pittsburgh, PA; Jiang Hong Bin, McGowan Inst for Regenerative Med, University of Pittsburgh, Pittsburgh, PA; Antonio D'Amore, William R Wagner, McGowan Inst for Regenerative Med, University of Pittsburgh the Heart and Vascular Inst, University of Pittsburgh Medical Center, Pittsburgh, PA

Mo3080/3080 - Identification of a Novel Sarcomeric TPM1 Variant in Familial Atrial Septal Defect 
Authors: Polakit Teekakirikul, University Pittsburgh Med Center, Pittsburgh, PA; Wenjuan Zhu, BGI, Shenzhen, China; Xinxiu Xu, University Pittsburgh Med Center, Pittsburgh, PA; Amanda M Smith, Indiana Univ Sch of Med, Indianapolis, IN; Chengdong Wang, The Chinese Univ of Hong Kong, Hong Kong, Hong Kong; George Gabriel, Daniel Sonnenberg, Anne Moreau de Bellaing, Michael X Wang, University Pittsburgh Med Center, Pittsburgh, PA; Honglan Gou, BGI, Shenzhen, China; Yijen L Wu, Abha Bais, Omar Khalifa, Maliha Zahid, University Pittsburgh Med Center, Pittsburgh, PA; Hui Zhao, The Chinese Univ of Hong Kong, Hong Kong, Hong Kong; Stephanie M Ware, Indiana Univ, Indianapolis, IN; Brian Feingold, Cecilia W Lo, University Pittsburgh Med Center, Pittsburgh, PA

Mo4086/4086 - Lrp1, an Endocytic Vesicle Trafficking Protein, is Associated With Congenital Heart Diseases - Through a "non-Autonomous" Action
Authors: Jiuann-Huey Ivy Lin, Children’s Hosp of Pittsburgh, Pittsburgh, PA; Anupma Jha, University of Pittsburgh, Pittsburgh, PA; Jacob McCleary, Timothy Feinstein, Cecilia Lo, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA

Mo4091/4091 - Dominant Mouse Mutagenesis Screen Unveils a Complex Genetic Architecture for Congenital Heart Disease 
Authors: Michael Wang, Tuantuan Tan, Univ of Pittsburgh, Pittsburgh, PA; Sara Hildebrand, Univ of Texas Southwestern Medical Ctr, Dallas, TX; Abha Bais, Sebastian Ho, Yiming Wang, Daniel Sonnenberg, Manisha Kukkillaya, Caleb Radomile, Lauren Meyer, William Devine, University of Pittsburgh, Pittsburgh, PA; Laura Reinholdt, The Jackson Lab, Bar Harbor, ME; Bruce Beutler, Univ of Texas Southwestern Medical Ctr, Dallas, TX; Yijen Wu, Cecilia Lo, University of Pittsburgh, Pittsburgh, PA

Mo1283/1283 - Incidence and Cause of Hospital Readmissions After Ischemic Ventricular Tachycardia Ablation
Authors: Rohit Rattan, Vikas K Singh, Prabhjot Bedi, University of Pittsburgh Medical Center, Monroeville, PA; Deepak Kumar Pasupula, Univ of Pittsburgh Medical Ctr, Pittsburgh, PA; Muhamad Bilal Munir, West Virginia Univ Heart and Vascular Inst, Morgantown, WV; Andrew Voigt, Evan Adelstein, Sandeep K Jain, Samir Saba, University of Pittsburgh Medical Center, Pittsburgh, PA

Mo1287/1287 - The Incidence of Perioperative Stroke Within 30 Days of Surgical Procedures: State Inpatient Database Study 
Authors: Khaled Al-Robaidi, Rami Al-Hader, Tudor Jovin, Ashutosh Jadhav, Parthasarathy Thirumala, University of Pittsburgh Medical Center, Pittsburgh, PA

Mo4181/4181 - Intrinsic Cardiomyocyte Mitochondrial Defects Underlie Cardiac Dysfunction and Heart Failure Risk Associated With Hypoplastic Left Heart Syndrome
Authors: Xinxiu Xu, Tuantuan Tan, Jiuann-Huey Ivy Lin, Phillips Adams, Xiaoqin Liu, Feinstein Timothy N, Omar Khalifa, University of Pittsburgh, Pittsburgh, PA; George A Porter Jr, Univ of Rochester Sch of Med and Dentistry, Rochester, NY; Sruti S. Shiva, Cecilia Lo, University of Pittsburgh, Pittsburgh, PA

Mo4034/4034 - Concomitant Fetal Heart and Brain MRI in Congenital Heart Disease Mouse Models With Sub-Nyquist Acquisition 
Authors: Yijen L Wu, University of Pittsburgh, Pittsburgh, PA; Anthony G Christodoulou, Cedars-Sinai Medical Ctr, Los Angeles, CA; Cecilia Lo, University of Pittsburgh, Pittsburgh, PA

Mo4036/4036 - Structural and Functional Investigation of Myocardial Fiber Architecture in Genetic Mouse Models of Heterodoxy and Situs Inverses Totalis 
Authors: Yijen L Wu, Xiaoqin Liu, Yu Chen, Nathan Salamacha, University of Pittsburgh, Pittsburgh, PA; Joyce Han, Dartmouth Coll, Hanover, NH; Daniel B Ennis, Univ of California Los Angeles, Los Angeles, CA; Sameh Tadros, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA; Cecilia Lo, University of Pittsburgh, Pittsburgh, PA

170 - Tead1 is Required for Cardiomyocyte Proliferation 
Authors: Ruya Liu, Rajaganapathi Jagannathan, Feng Li, Jeongkyung Lee, Vijay K Yechoor, Mousumi Moulik, University of Pittsburgh, Pittsburgh, PA

533 - Tead1 - a Novel Cell-Autonomous Regulator of Mitochondrial Function in Cardiomyocytes 
Authors: Ruya Liu, Rajaganapathi Jagannathan, Feng Li, Jeongkyung Lee, Vijay K Yechoor, Mousumi Moulik, University of Pittsburgh, Pittsburgh, PA

Mo1357/1357 - a Rare MEGF8 variant is Involved in the Genetic Risk for Transposition of the Great Arteries 
Authors: Anne Moreau de Bellaing, Kylia Williams, Sally Li, Abha S Bais, Cullen B Young, Cecilia W Lo, University of Pittsburgh School of Med, Pittsburgh, PA

Mo4045/4045 - Nitrite Treatment in Hypoxia improves Zebrafish Cardiac and Fin Regeneration 
Authors: Elizabeth R Rochon, Jianmin Xue, Paola Corti, Mark T Gladwin, University of Pittsburgh, Pittsburgh, PA

Mo1298/1298 - Should Paramedics Withhold Nitroglycerin in Patients With Prehospital Chest Pain Who Are Tachycardiac? 
Authors: Mohammad Alhamaydeh, Conemaugh Memorial Medical Ctr, Johnstown, PA; Ziad Faramand, Christian Martin-Gill, Clifton Callaway, Salah Al-Zaiti, University of Pittsburgh, Pittsburgh, PA

Mo4143/4143 - Cryoem Analysis in Cardiac Isolated Mitochondria Reveals New Insights for CsA and mPTP Activation
Authors: Jasiel O Strubbe, Jason Schrad, Michigan State Univ, East Lansing, MI; James F Conway, University of Pittsburgh, Pittsburgh, PA; Kristin N Parent, Jason N Bazil, Michigan State Univ, East Lansing, MI

Mo1318 / 1318 - Myocardial RNA Sequence Analyses Throughout the Course of Mouse Cardiac Laminopathy Identify Differential Expressions of the Key Genes for Cell Cycle Control and Mitochondrial Function
Authors: Zhili Shao, Cleveland Clinic, Cleveland, OH; Wonshill Koh, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA; Ying Ni, W. H. Wilson Tang, Cleveland Clinic, Cleveland, OH

Negative Regulation of Mitophagy by Deubiquitinases 
Author: Toren Finkel, Pittsburgh, PA 

Functional Specialization of Endothelium and Myo-endothelial Junction
Author: Adam C. Straub, Pittsburgh, PA