UPMC Heart and Vascular Experts Present at the American Heart Association’s Annual Scientific Sessions

The UPMC Heart and Vascular Institute was well-represented at the American Heart Association’s Scientific Sessions in Anaheim, CA on Saturday, Nov. 11 – Wednesday, Nov. 15. Faculty research was presented in both oral and abstract presentations including:

Saturday, November 11, 2017

Session RESS.CVS.02 – Main Event: Outcomes of Cardiac Arrest Survivors With ICDs
Rehabilitation for Cardiac Arrest Survivors with ICDs
Presented by: Jon C. Rittenberger

Session RESS.CVS.06 – Main Event: Prognostication After Resuscitation
Prognostication After Major Trauma and TBI
Presented by: Lori A. Shutter

Sunday, November 12, 2017

Session SA.JS.783 – Innovation in Cardiac Surgery: From Imaginative Research to Transformative Clinical Therapy (AHA/The Society of Thoracic Surgeons Joint Session)
Should Bicuspid Valves Ever Be Repaired?
Presented by: Thomas Gleason

Session QU.APS.01 – Quality of Care: Acute and Chronic CAD
Predictors of Emergency Medical Personnel’s Decision to Transmit or Not to Transmit the Prehospital 12-Lead ECG of Patients With Suspected Acute Myocardial Infarction Presented by: Amber DeSantis, Parker Landis, Mohammad Alrawashdeh, Christian Martin-Gill, Clifton Callaway, Salah S Al-Zaiti

Session NR.APS.02 – Monitoring and ICDs: Patients With ACS and CABG
The Prevalence of Secondary Repolarization Abnormalities Confounding the Electrocardiographic Diagnosis of Acute Myocardial Ischemia in Patients Presenting With Chest Pain
Presented by: Diana Rivero, Mohammad Alhamaydeh, Christian Martin-Gill, Clifton Callaway, Barbara Drew, Salah S Al-Zaiti

Time of Day and Day of Week Variations in Chest Pain Encounters at the Prehospital Setting
Presented by: Mohammad Alhamaydeh, Mohammad Alrawashdeh, Christian Martin-Gill, Clifton Callaway, Salah S Al-Zaiti

Incidence and Predictors of Delaying Seeking Emergent Medical Care Among Patients With Suspected Acute Coronary Syndrome
Presented by: Stephanie Frisch, Christian Martin-Gill, Mohammed Alrawashdeh, Clifton Callaway, Salah Al-Zaiti

Session CH.APS.01 – Fetal Cardiology
Fetal Hemodynamics Predict Postnatal Regional and Microstructural Brain Alterations in Complex Congenital Heart Disease
Presented by: Jodie K. Votava-Smith, Jay D. Pruetz, Nhu Tran, Vincent Lee, Hollie Lai, Vincent J. Schmithorst, Lisa B. Paquette, Ashok Panigrahy

Session CH.RFO.03 – Transitional Research in CHD
Altered Placental Bold Signal is Associated With Reduced Fetal Brain Functional Connectivity in Congenital Heart Disease
Presented by: Vidya Rajagopalan, Vincent K Lee, William Reynolds III, Alex El-Ali, Jenna Schabdach, Julia Wallace, Alexandria Zahner, Rafael Ceschin, Jodie Votava-Smith, Jacqueline Weinberg, Vincent J Schmithorst, Ashok Panigrahy

Session HF.APS.08 – Heart Failure and Cardiomyopathies: General Topics IIII
Are Echocardiogram and Magnetic Resonance Imaging (MRI) Comparable in Measuring Maximal Septal Thickness in Children With Hypertrophic Cardiomyopathy (HCM)?

Presented by: Sonya Kirmani, Pamela K Woodard, Ling Shi, Charles E Canter, Steven D Colan, Elfriede Pahl, Jeffrey A Towbin, Steven A Webber, Joseph W Rossano, Melanie D Everitt, Kimberly M Molina, Paul F Kantor, John L Jefferies, Brian Feingold, Linda J Addonizio, Stephanie M Ware, Wendy K Chung, Jean A Ballweg, Teresa M Lee, Hiedy Razoky, Jason D Czachor, Fatima I Lunze, Edward Marcus, James D Wilkinson, Steven E Lipshultz

Session CH.RFO.03 – Translational Research in CHD
Identification of a Novel TPM1 Mutation in Congential Atrial Septal Defect With Autosomal Dominant Inheritance
Presented by: Polakit Teekakirikul, Wenjuan Zhu, Michael X Wang, Amanda M Smith, Honglan Gou, Abha Bais, Omar Khalifa, Maliha Zahid, Stephanie M Ware, Brian Feingold, Cecilia W Lo

Session IN.APS.05 – Percutaneous Non-Coronary Cardiac Intervention
Denovo Pulmonary Hypertension After Transcatheter Aortic Valve Replacement is Associated With Higher Mortality – The Importance of Continued Assessment
Presented by: Joao L Cavalcante, Islam Abdelkarim, Jeffrey Xu, Michael Sharbaugh, Andrew D Althouse, Dustin Kliner, Ibrahim Sultan, Frederick Crock, Matthew E Harinstein, William E Katz, Joon S Lee, John T Schindler, Thomas G Gleason

Session RESS.AOS.11A – Oral Abstracts-Cardiac Arrest Epidemiology
Long-Term Outcomes Disparities in Survivors of Cardiac Arrest Presented by: Patrick J Coppler, Jonathan Elmer, Jon C Rittenberger, Clifton W Callaway, David J Wallace

Session Va.APS.01 – Latest in Pulmonary Embolism, Injury and Non Group 1 Pulmonary Hypertension
Effect of Remodulin in Pulmonary Hypertension Associated With Heart Failure With Preserved Ejection Fraction (PH-HFpEF) Presented by: Jian Hu, Ana L Mora, Yen-Chun Charly Lai

Monday, November 13, 2017

Session SA.APS.05 – Thoracic Aortic Surgery II
Characterization of Type B Acute Aortic Dissection Patients With Presenting Spinal Cord Ischemia
Presented by: Jonathan Silverberg, Thomas G Gleason, Maral Ouzounian, Reed E Pyeritz, Marek P Ehrlich, Takeyoshi Ota, Eduardo Bossone, Stuart Hutchison, Truls Myrmel, Mark D Peterson, Gilbert R Upchurch Jr, Daniel G Montgomery, Eric M Isselbacher, Christoph A Nienaber, Kim A Eagle, Himanshu J Patel

Session GE.APS.03 – Genetics and Genomics Using Big Data
GWAS Identifies GPC6 as a Novel Predictor of Arrhythmia in Heart Failure
Presented by: Haider Mehdi, Ryan L Boudreau, Rebecca Gutmann, Patrick Breheny, Gina M Morgan, Alexander M Greiner, Heather L Bloom, Alaa Shalaby, Raul Weiss, Samuel C Dudley, Samir Saba, Dennis M McNamara, Madhurmeet Singh, Steven A Lubitz, Patrick T Ellinor, Barry London

Session VA.AOS.1970 – Not Home Alone: Mechanistic Insights into Associated Pulmonary Hypertension
Proinflammatory Monocytes and Fibrotic Alveolar Macrophages Are Associated With Progression of Pulmonary Arterial Hypertension in a Primate Model of Human Immunodeficiency Virus Infection
Presented by: Finja Schweitzer, Rebecca Tarantelli, Marc Simon, Whitney Rabacal, Emily Rayens, Karen Norris

Session AT.APS.22 – Vascular Science and Hypertension: Experimental
Longitudinal Assessment of Hemodynamic Changes in a NonHuman Primate Model of Human Immunodeficiency Virus Associated Pulmonary Arterial Hypertension
Presented by: Rebecca A Tarantelli, Marc A Simon, Rebecca Vanderpool, Ian Christman, Finja Schweitzer, Heather Kling, Toni Ann Zullo, Eoin J Carney, Brian Lopresti, Karen A Norris

Session HF.APS.18 – CHF/Cardiomyopathy: Novel Insights
NAT2 Genotype and Outcomes in the Genetic Sub-Study of the African American Heart Failure Trial (AHeFT)

Presented by: Barry E Bleske, Hao-Jie Zhu, Karen Hanley-Yanez, Indrani Halder, Dennis M McNamara

Session RESS.APS.03.07 – ReSS Poster Session Day 3, Section 07
Clinical Outcomes and Mortality Impact of Hyperbaric Oxygen Therapy in Patients With Carbon Monoxide Poisoning
Presented by: Jason J Rose, Seyed M Nouraie, Marc C Gauthier, Anthony F Pizon, Melissa I Saul, Michael P Donahoe

Session RESS.APS.03.13 – ReSS Poster Session Day 3, Section 13
Hypothermic to Ischemic Ratio as a Predictor of Good Functional Outcome From Out-of-Hospital Cardiac Arrest in the Resuscitation Outcomes Consortium Amiodarone Lidocaine or Placebo Study
Presented by: Kelly N Sawyer, Andrew Humbert, Brian G Leroux, Graham Nichol, Peter J Kudenchuck, Mohamud R Daya, Brian Grunau, Henry E Wang, Joseph P Ornato, Jon C Rittenberger, Tom P Aufderheide, Lynn Wittwer, M Riccardo Colella, Michael Austin, Takahisa Kawano, Debra Egan, Neal Richmond, Veer D Vithalani, Damon Scales, Andrew J Baker, Laurie J Morrison, Michael C Kurz

Session RESS.APS.03.11 – ReSS Poster Session Day 3, Section 11
Times to Recovery in Individual Domains of the Cerebral Performance Category-Extended
Presented by: Katharyn L Flickinger, Melissa J Repine, Allison C Koller, Margo B Holm, Elizabeth R Skidmore, Clifton W Callaway, Jon C Rittenberger

Session RESS.APS.03.13 – ReSS Poster Session Day 3, Section 13
Delayed Left Atrial Decompression is Associated With Prolonged Duration of Veno-arterial Extracorporeal Membrane Oxygenation Support: Results of a Multicenter Pediatric Interventional Cardiology Early Career Society (PICES) Study Presented by: Jeffrey D. Zampi, Fares Alghanem, Sunkyung Yu, Ryan Callahan, Christopher L. Curzon, Jeffrey W. Delaney, Robert G. Gray, Carrie E. Herbert, Ryan A. Leahy, Ray Lowery, Sara K. Pasquali, Priti M. Patel, Diego Porras, Shabana Shahanavaz, Ravi R. Thiagarajan, Sara M. Trucco, Mariel E. Turner, Surendranath R. Veeran Reddy, Shawn C. West, Wendy Whiteside, Bryan H. Goldstein

Session RESS.AOS.14 – Dickinson W. Richards Memorial Lecture
Epidemiology of Out-of-Hospital Cardiac Arrest Within the Resuscitation Outcomes Consortium From 2011 to 2015: Improved Survival Though Site Differences Persist
Presented by: Dana M Zive, Robert Schmicker, Mohamud Daya, Peter Kudenchuk, Jon C Rittenberger, Tom Aufderheide, Gary Vilke, Jim Christenson, Jason Buick, Ken Kaila, Susanne J May, Thomas Rea, Laurie J Morrison

Session SA.CVS.762 – Hot Topics in Cardiovascular Surgery
Toward Precision/Molecular Medicine: Determinants of Surgical Decision Making in Bicuspid Valve Disease
Presented by: Thomas Gleason

Session LB.APS.09 – Clinical Risk Factors and Biomarkers in Risk Prediction
Evaluating the Diagnostic Accuracy of Clinical Risk Scores to Detect Acute Coronary Syndrome in Patients Evaluated at the Emergency Department for a Chief Complaint of Chest Pain
Presented by: Ziad Faramand, Mohammad Alrawashdeh, Christian Martin-Gill, Clifton Callaway, Salah S Al-Zaiti

Session HF.APS.25 – New Insights into Heart Failure Biomarkers
Interaction of G-Protein Beta 3 Subunit (GNB3) and G-Protein Receptor Kinase 5 (GRK5) Genotypes Impacts Heart Failure Outcomes in African Americans
Presented by: Karen Hanley-Yanez, Clyde W Yancy, Anne L Taylor, Arthur M Feldman, Dennis M McNamara

Session GE.APS.07 – Genomics of Cardiovascular Risk
Contribution of ABCA1 Genetic Variation to Plasma Lipid Levels in Non-Hispanic White Americans
Presented by: Vipavee Niemsiri, Xingbin Wang, Zaheda H Radwan, Dilek Pirim, Indrani Halder, Steven E Reis, John E Hokanson, Richard F Hamman, M Michael Barmada, Eleanor Feingold, F Yesim Demirci, M Ilyas Kamboh

Session CH.APS.13 – Congenital Heart Disease and Pediatric Cardiology: General Topics
Impaired Pre-Operative Cerebral Autoregulation is Associated With Functional Brain Dysmaturation in Neonatal Congenital Heart Disease
Presented by: Jodie K Votava-Smith, Vincent J. Schmithorst, Nhu Tran, Sadaf Soleymani, Justin Abbott, Vincent Lee, Sylvia del Castillo, Hollie A. Lai, Lisa B. Paquette, Ashok Panigrahy

Session EA.RFO.04 – State of the Art: Topical Trial Results From Electrophysiology
Wealth Brings Health: Annual Income is Associated With Health-related Quality of Life in Atrial Fibrilation
Presented by: Emily N Guhl, Andrew D Althouse, Michael Sharbaugh, Courtney L Schlusser, Jared W Magnani

Session HF.APS.16 – Heart Failure and Cardiomyopathies: General Topics IV
Sex Differences and Outcomes of Heart Failure Admissions Stratified by Left Ventricle Ejection Fraction
Presented by: Ahmad Masri, Andrew D Althouse, Gavin Hickey, Jeffrey McKibben, Ravi Ramani, Michael Mathier, Joon Lee, Oscar Marroquin, Suresh Mulukutla

Tuesday, November 14, 2017

Session HF.APS.40 – Insights into CHF Risk Factors and Outcomes
Cytokine Elevations and Outcomes in Peripartum Cardiomyopathy
Presented by: Dennis M McNamara, Karen Hanley-Yanez, Penelope Morel, Charles McTiernan

Session HF.APS.33 – Novel Insights Into the Diagnosis and Prognosis of Cardiomyopathy and Heart Failure
Cellular Immune Activation and Breastfeeding in Peripartum Cardiomyopathy
Presented by: Agnes Koczo, Amy Marino, Arun Jeyabalan, Uri Elkayam, Leslie Cooper, James Fett, Charles McTiernan, Penelope Morel, Karen Hanley-Yanez, Dennis McNamara

Session: IM.CVS.732 – TAVR: Imaging Highlights
Echocardiography Assessment of Critical Aortic Stenosis prior to TAVR
Presented by: Joao L Cavalcante

Session ST.AOS.888 – Stroke Oral Abstracts
Biventricular Cardiac Dysfunction in Neurocardiac Injury Assessed by Strain Imaging is Associated With In Hospital Mortality in Subarachnoid Hemorrhage
Presented by: Nobuyuki Kagiyama, Masataka Sugahara, Nina E. Hasselberg, Eliabeth A. Crago, Theodore F. Lagattuta, Khalil Moh’d Yousef, Marilyn T. Hravnak, John Gorcsan III

Session IM.APS.19 – Echocardiography: Hypertension, Coronary Artery Disease, and Function
Biventricular Strain as a New Marker of Severity of Neurocardiac Injury in Patients With Subarachnoid Hemorrhage
Presented by: Nobuyuki Kagiyama, Masataka Sugahara, Nina E. Hasselberg, Eliabeth A. Crago, Theodore F. Lagattuta, Khalil Moh’d Yousef, Marilyn Hravnak, John Gorcsan III

Session EP.RFO.42 – AHA’s Life Simple 7 and 2020 Goals
The AHA Life Simple 7: An Assessment Using the Behavorial Risk Factor Surveillance System 2011-2015
Presented by: Andrew D Althouse, Michael S Sharbaugh, Floyd W Thoma, Joon Sup Lee, Vince M Figueredo, Suresh R Mulukutla

Session CH.CVS.682 – VAD to Transplant: Challenges and Insights
Are we too sensitive? Challenges With managing the Sensitized Patient
Presented by: Brian Feingold

Session WS.APS.04 – Race, Sex, SES: Disparities in Cardiovascular Care
African-American Ethnicity, Risk Variables, Coronary Artery Disease, and Long-Term Prognosis in Women: The National Heart, Lung, and Blood Institute Sponsored Women’s Ischemia Syndrome Evaluation Study
Presented by: Pankaj Malhotra, Galen Cook-Wiens, Carl J Pepine, Eileen M Handberg, Steven E Reis, Nathaniel Reichek, Vera Bittner, Sheryl F Kelsey, Reddy Sailaja Marpuri, George Sopko, C Noel Bairey Merz