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UPMC Children’s Heart Institute Congratulates Bernhard Kühn, MD, on American Pediatric Society Membership

December 17, 2021

The Heart Institute at UPMC Children’s Hospital of Pittsburgh congratulates Bernhard Kühn, MD, on becoming a new member of the American Pediatric Society (APS) as part of its 2022 class of new members.

Founded in 1888, the APS is the first and most prestigious academic pediatric organization in North America. Dr. Kühn and the other new members will be recognized during the APS Presidential Plenary at the Pediatric Academic Societies 2022 Meeting to be held April 21-25, 2022, in Denver, Colorado.

APS members are recognized child health leaders of extraordinary achievement who work together to shape the future of academic pediatrics. New members are nominated by current members through a process that recognizes individuals who have distinguished themselves as child health leaders, teachers, scholars, policymakers, and clinicians.

More About Dr. Kühn

Bernhard Kühn, MD, is a Professor of Pediatrics and Cell Biology, Director of Research at the UPMC Children’s Hospital Heart Institute, and the Director of the Pediatric Institute for Heart Regeneration and Therapeutics. Dr. Kühn also is an Associate Director of the Richard King Mellon Foundation Institute for Pediatric Research at UPMC Children's and an Investigator at the McGowan Institute for Regenerative Medicine. 

Dr. Kühn is an internationally-respected researcher whose focus is devoted to understanding the basic mechanisms of heart growth and regeneration and developing approaches to induce heart muscle cell regeneration to translate this work into novel methods for treating congenital cardiac lesions and heart failure.

A pioneer in this area of study, Dr. Kühn is the recipient of numerous grants and awards, including the American College of Cardiology's prestigious Young Investigator Award, the Basil O'Connor Award from the March of Dimes Birth Defects Foundation, and Scientist Development Grant from the American Heart Association.

Select Recently Published Research From Dr. Kühn

El Khoudary SR, Fabio A, Yester JW, Steinhauser ML, Christopher AB, Gyngard F, Adams PS, Morell VO, Viegas M, Da Silva JP, Da Silva LF, Castro-Medina M, McCormick A, Reyes-Múgica M, Barlas M, Liu H, Thomas D, Ammanamanchi N, Sada R, Cuda M, Hartigan E, Groscost DK, Kühn B. Design and Rationale of a Clinical Trial to Increase Cardiomyocyte Division in Infants With Tetralogy of Fallot. Int J Cardiol. 2021 Sep 15; 339: 36-42.

Yester JW, Liu H, Gyngard F, Ammanamanchi N, Little KC, Thomas D, Sullivan MLG, Lal S, Steinhauser ML, Kühn B. Use of Stable Isotope-Tagged Thymidine and Multi-Isotope Imaging Mass Spectrometry (MIMS) for Quantification of Human Cardiomyocyte Division. Nat Protoc. 2021 Apr; 16(4):1 995-2022.

Han L, Choudhury S, Mich-Basso JD, Ammanamanchi N, Ganapathy B, Suresh S, Khaladkar M, Singh J, Maehr R, Zuppo DA, Kim J, Eberwine JH, Wyman SK, Wu YL, Kühn B. Lamin B2 Levels Regulate Polyploidization of Cardiomyocyte Nuclei and Myocardial Regeneration. Dev Cell. 2020 Apr 6; 53(1): 42-59.e11. 

Liu H, Zhang CH, Ammanamanchi N, Suresh S, Lewarchik C, Rao K, Uys GM, Han L, Abrial M, Yimlamai D, Ganapathy B, Guillermier C, Chen N, Khaladkar M, Spaethling J, Eberwine JH, Kim J, Walsh S, Choudhury S, Little K, Francis K, Sharma M, Viegas M, Bais A, Kostka D, Ding J, Bar-Joseph Z, Wu Y, Yechoor V, Moulik M, Johnson J, Weinberg J, Reyes-Múgica M, Steinhauser ML, Kühn B. Control of Cytokinesis by Β-Adrenergic Receptors Indicates An Approach for Regulating Cardiomyocyte Endowment. Sci Transl Med. 2019 Oct 9; 11(513): eaaw6419.

Liu H, Bersell K, Kühn B. Isolation and Characterization of Intact Cardiomyocytes From Frozen and Fresh Human Myocardium and Mouse Hearts. Methods Mol Biol. 2021; 2158: 199-210.  

Han L, Mich-Basso J, Kühn B. Generation of Human Induced Pluripotent Stem Cells and Differentiation Into Cardiomyocytes. Methods Mol Biol. 2021; 2158: 125-139.