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Associate Professor of Medicine
UPMC Montefiore Hospital, NW628
3459 Fifth Avenue
Pittsburgh, PA 15213
BS, Chemistry, St. Joseph's University, Philadelphia, 1986
MD, Thomas Jefferson Medical College, 1990
Residency, Internal Medicine, Barnes Hospital, Washington University, 1993
Fellowship, Allergy/Immunology, National Institute of Allergy and Infectious Diseases, 1998
Fellowship, Critical Care/Pulmonary Medicine, NIH Bethesda and Johns Hopkins University, 2002
CMV infection remains the most common infection in lung transplant recipients (LTRs) and a major cause of morbidity and mortality. Dr McDyer’s research investigates T-bet, the T cell transcriptional factor to determine if it is necessary for protective CMV-specific immunity during acute and chronic CMV infection. To test this he uses both the murine CMV (MCMV) pulmonary infection model and the LTR cohort to study the role of T-bet in pulmonary and systemic CMV host defense and the development of protective T cell memory.