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In this issue of Neurosurgery News, Drs. Nowicki, Gross, and Friedlander describe a novel in vitro model developed to better understand the formation of cerebral aneurysms.

Drs. McDowell and Wecht describe a department-sponsored study that evaluated the exclusive use of fixed pressure valves for cerebrospinal fluid diversion in an adult cohort. 

Dr. Monaco and colleagues demonstrate that rates of auditory preservation in elderly patients undergoing Gamma Knife® radiosurgery for vestibular schwannomas are the same as for younger patients.

Dr. Amankulor and colleagues demonstrate the continued importance of bench-to-basic science research to develop new strategies for immunotherapy against glioblastomas. Drug delivery to the central nervous system has always presented a significant challenge due to the blood-brain barrier. Dr. Faraji describes important advances that have been developed to improve the control of drug delivery to the brain using electrokinetic transport. 

Educational Objectives:

Upon completion of this activity, participants should be able to:

  • Describe shunt malfunction etiologies and recognize the socioeconomic costs associated
  • Explain differences in cerebrospinal fluid diversion needs based on etiology
  • Identify basic principles of electrokinetic transport, analyze the current delivery methods, and recognize their limitations
  • Describe frequency of VS intervention
  • Recognize effectiveness of GK in elderly and recall hearing preservation in GK VR treatment
  • Identify cerebral aneurysms in patients and explain treatment options
  • Analyze the prevalence of cerebral aneurysms and improve patient outcomes by raising awareness of the disease
  • Explain glioma genetics and implement medical management of high-grade gliomas
  • Recall tumor immune environments

Disclosures:

Nduka Amankulor, Michael McDowell, Edward Monaco III, Kamil W. Nowicki, Alp Ozpinar, Matthew Pease, Aparna Rao, Aleksandra Safonova, Daniel Wecht, and Xiaoran (Zel) Zhang have reported no relevant relationships with entities producing health care goods or services.

 

Dr. Amir Faraji has financial interests with the following entity or entities producing health care goods or services as indicated below:

  • Grant/Research Support: Copeland Fund of the Pittsburgh Foundation

Dr. Bradley Gross has financial interests with the following entity or entities producing health care goods or services as indicated below:

  • Consultant: MicroVention, Inc. 

Dr. Robert Friedlander has financial interests with the following entity or entities producing health care goods or services as indicated below:

  • Consultant: NeuBase Therapeutics 
  • Other: Scientific Advisory Board Consultant for DiFusion, Inc.

Accreditation Statement:

The University of Pittsburgh School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The University of Pittsburgh School of Medicine designates this enduring material for a maximum of .50 AMA PRA Category 1 Credits. Each physician should only claim credit commensurate with the extent of their participation in the activity. Other health care professionals are awarded (.05) continuing education units (CEU) which are equivalent to .50 contact hour.

For your credit transcript, please access our website 4 weeks post-completion at http://ccehs.upmc.com and follow the link to the Credit Transcript page. If you do not provide the last 5 digits of your SSN on the next page you will not be able to access a CME credit transcript. Providing your SSN is voluntary.

Release Date: 2/27/2019 | Last Modified On: 2/27/2019 | Expires: 2/27/2020

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