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Julia Meade, MD, and Elena Kessler, MS, LCGC, describe the genetic basis of cancer and differentiate between somatic and gremlin mutations. They also present types of cancers seen in children and suspicious family histories that raise concern for an inherited cancer predisposition syndrome (ICPS).

Educational Objectives

Upon completion of this activity, participants should be able to:

  • Explain the role family history contributes to a cancer genetics referral in children diagnosed with cancer
  • Recognize the prevalence of ICPS amongst children diagnosed with cancer
  • Describe the indication for a cancer genetics referral in children


Dr.Meade and Ms. Kessler have reported no relevant relationships with entities producing health care goods or services.

All presenters' disclosures of relevant financial relationships with any entity producing, marketing, re-selling, or distributing health care goods or services used on or consumed by patients is listed above. No other planners, members of the planning committee, speakers, presenters, authors, content reviewers, and/or anyone else in a position to control the content of this education activity have relevant financial relationships to disclose.

Accreditation Statement

In support of improving patient care, the University of Pittsburgh is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

The University of Pittsburgh designates enduring material activity for a maximum of 0.75 AMA PRA Category 1 Credit[s]™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Other health care professionals will receive a certificate of attendance confirming the number of contact hours commensurate with the extent of participation in this activity.

For your credit transcript, please access our website four weeks postcompletion at and follow the link to the Credit Transcript page.

Release Date: 1/17/2020 | Last Modified On: 1/17/2020 | Expires: 1/18/2021


This course has been expired.