About Our Pediatric Oncology Program

The Division of Pediatric Hematology/Oncology at UPMC Children’s Hospital of Pittsburgh is the largest, most comprehensive pediatric cancer and blood disease center in western Pennsylvania, eastern Ohio, and northern West Virginia. The Division of Pediatric Hematology/Oncology provides diagnosis, treatment, and complete follow-up for children, adolescents, and young adults with cancer and blood disorders.

UPMC Children’s Hospital of Pittsburgh has been a member of the Children's Oncology Group (COG), a multi-institutional pediatric cancer research organization sponsored by the National Cancer Institute, since 1961. Many of Children’s Hospital’s physicians hold key positions in the COG and are active in developing new cancer treatment strategies. Membership in this prestigious organization allows Children’s to offer state-of-the-art therapy to children with all forms of childhood cancer.

All patients with cancer are eligible to participate in current Children’s Oncology Group (COG) protocols — studies of the most promising and newest cancer therapies.

Leading Experts

Children's Hematology/Oncology staff provides comprehensive, family-focused care for children diagnosed with all kinds of childhood cancer and blood-related diseases. The Hematology/ Oncology team includes highly skilled physicians, psychologists, physicians’ assistants, nurse practitioners, nurses, pharmacists, technicians, social workers, and child life specialists. The breadth and depth of the division’s expertise is strengthened by its collaboration with other subspecialties at Children’s, including:

  • Blood and Marrow Transplantation and Cellular Therapies
  • General and Thoracic Surgery
  • Neurosurgery
  • Ophthalmology
  • Orthopaedic Surgery
  • Pathology
  • Radiology
  • Urology


Children’s Hematology/Oncology Division also has highly specialized and nationally recognized treatment teams in place to care for children with brain tumors, and patients who require bone marrow and stem cell transplantation. All outpatients are treated in the Marty Ostrow Hematology/Oncology Treatment Center, which has all the necessary facilities for evaluating and treating patients. Hospitalized patients are treated on a dedicated hematology/oncology unit, and both the inpatient and outpatient units are staffed by specially trained personnel.

Children’s is also one of a handful of pediatric hospitals nationwide with its own on-site Radiation Oncology Department.


The research done in the Division of Pediatric Hematology/Oncology is supported by a number of organizations including the Children's Oncology Group (COG) and the National Institutes of Health (NIH). Researchers have participated in a wide variety of projects, including:

  • Immunotherapy for childhood gliomas
  • Treatment of histiocyctic sarcoma
  • C-myc oncoprotein and tumor-derived endothelial cells

Featured Program

The Sickle Cell and Hematology Program provides comprehensive health care, emphasizing preventive medical care to children with sickle cell anemia and related blood disorders. Sickle cell patients can also be seen at Children's Specialty Care Center in Hermitage, Pa.

UPMC Children’s Hospital of Pittsburgh is one of four medical centers funded by Pennsylvania’s Division of Maternal and Child Health to receive newborn sickle cell screening test results.

Division of Blood and Marrow Transplantation and Cellular Therapies provides state-of-the-art stem cell transplants for patients with very high risk malignancies, blood disorders, and immunodeficiency states. The Coagulation Program has dedicated personnel to diagnose and treat bleeding and clotting disorders.

All of the comprehensive patient care programs offer support services for the psychosocial needs of patients and their families. A counselor/nurse, child-life specialist, and social worker are all integral components of the health care team.

Pediatric Oncology Publications from UPMC